IC50: 5.71 µM (PCAF/H31-21)[1].
NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].
NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1].
Cell Proliferation Assay[1]
| Cell Line: | SK-N-SH, HCT116 cells |
| Concentration: | 25 µM |
| Incubation Time: | 72 h |
| Result: | Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 19.2 µM and growth inhibition of 29%, respectively. |