Paeonolsilate (sodium) can inhibit ox-LDL-induced macrophage foam cell formation and inflammation in atherosclerosis. Paeonolsilate (sodium) inhibits NF-κB activation and oxidative stress response induced by ox-LDL. Paeonolsilate (sodium) can be studied in anti-atherosclerosis research [1].
References:
[1]. Wenbo Fu, et al., (2016). Sodium paeonolsilate inhibits ox-LDL induced macrophage foam cell formation andinflammation in atherosclerosis. Int J Clin Exp Med 2016;9(2):1051-1061.
[2]. Kushiku, K., et al., (2001). Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high-frequency preganglionic stimulation at the canine cardiac sympathetic ganglia. Circulation research, 88(1), 110–116.
References:
[1]. Wenbo Fu, et al., (2016). Sodium paeonolsilate inhibits ox-LDL induced macrophage foam cell formation andinflammation in atherosclerosis. Int J Clin Exp Med 2016;9(2):1051-1061.
[2]. Kushiku, K., et al., (2001). Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high-frequency preganglionic stimulation at the canine cardiac sympathetic ganglia. Circulation research, 88(1), 110–116.