GLPBio

COX

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products Related to COX(306)

  • GC68849 structure
    GC68849Celecoxib-d3
    CAS: 544686-18-2
    Purity: >99.00%

    Celecoxib-d3 es la forma deuterada de Celecoxib. Celecoxib es un inhibidor selectivo de COX-2 con una IC50 de 40 nM.

  • GC69640 structure
    GC69640Oxaprozin-d4
    Purity: >99.00%

    Oxaprozin-d4 es la forma deuterada del Oxaprozin.

  • GC69699 structure
    GC69699Phenylbutazone-13C12
    CAS: 1325559-13-4
    Purity: >99.00%

    Phenylbutazone-13C12 es Phenylbutazone marcado con 13C12. Phenylbutazone es un cofactor reductor efectivo de la prostaglandina H sintasa (PHS) y la peroxidasa. Es una toxina hepática y un antiinflamatorio no esteroideo (AINE). Phenylbutazone induce la expresión de proteína muscular ciega tipo 1 (MBNL1), lo que tiene potencial para investigar la espondilitis anquilosante.

  • GC70218 structure
    GC70218Cavidine
    CAS: 32728-75-9

    Cavidine ((+)-Cavidine) es un inhibiselectivo de la COX-2 que posee actividad antiinflamatoria.

  • GC70553 structure
    GC70553Pelubiprofen
    CAS: 69956-77-0
    Purity: >99.00%

    Pelubiprofen, un fármaco antiinflamno esteroideactivo por vía oral, es un miembro de la familia del ácido 2-arilpropiónico y tiene efectos relativamente selectivos sobre la actividad de la COX-2.

  • GC70778 structure
    GC70778Indazole-Cl
    CAS: 848142-62-1

    Indazole-Cl (Ind-Cl) es un receptor de estrógeno (ER)- − agonista específico con efecto inflamatorio.

  • GC71602 structure
    GC71602Propyphenazone-d3
    CAS: 162935-29-7
    Purity: >99.00%

    Propyphenazone-d3 es el deuterio etiquetado propifenazona.

  • GC72794 structure
    GC72794Flobufen
    CAS: 112344-52-2

    Flobufen (VUFB 16066) es un agente antiinflamno esteroidey un agente inhibide la ciclooxigen(COX) y la 5-lipoxigenasa (5-LOX).

  • GC74187 structure
    GC74187Salicylic acid-13C6
    CAS: 1189678-81-6
    Purity: >97.00%

    Salicylic acid-13C6 es el ácido salicílico marcado con 13c.

  • GC79363 structure
    GC79363VU0487836
    CAS: 1632301-78-0
    Purity: >99.50%

    VU0487836 is a selective cyclooxygenase-1 ( COX-1 ) inhibitor with an IC 50 of 0.36 μM against ovine-derived COX-1.

  • GC79364 structure
    GC79364Desmethyl etoricoxib
    CAS: 202409-31-2
    Purity: >99.50%

    Desmethyl etoricoxib (example 21) is a selective COX-2 inhibitor with an IC 50 of 1 μM in whole blood.

  • GC79365 structure
    GC79365Bis[2-(4-hydroxyphenylthio)ethoxy]methane
    CAS: 93589-69-6
    Purity: >99.00%

    Bis[2-(4-hydroxyphenylthio) ethoxy]methane (DD-70) is a Bisphenol A substitute and a COX-1 inhibitor.

  • GC79459 structure
    GC79459EGFR/COX-2-IN-3
    CAS: 3121638-16-9
    Purity: >99.50%

    EGFR/COX-2-IN-3 is a selective EGFR / COX-2 dual inhibitor with IC 50 values of 0.098 μM and 0.05 μM, respectively.

  • GC80408 structure
    GC80408Meloxicam- 13 C 6
    Purity: >98.00%

    Meloxicam -13C6 is 13 C 6 -labeled Meloxicam.

  • GC80410 structure
    GC804104'-Acetoxy resveratrol
    CAS: 411233-11-9
    Purity: >99.50%

    4'-Acetoxy resveratrol is a Resveratrol derivative.

  • GC80415 structure
    GC80415(S)-Flurbiprofen-d 3
    Purity: >98%

    (S)-Flurbiprofen-d3 (Esflurbiprofen-d3) is the deuterium labeled (S)-Flurbiprofen.

  • GC80491 structure
    GC804914-Methylamino antipyrine-d 3 -1
    CAS: 1246820-06-3
    Purity: >98%

    4-Methylamino antipyrine-d 3 -1 is the deuterium labeled 4-Methylamino antipyrine-1.

  • GC81403 structure
    GC81403Allyl thiosulfate
    CAS: 6363-01-5
    Purity: >99.50%

    Allyl thiosulfate (Sodium 2-propenyl thiosulfate) is found in Allium plants such as garlic and onion.

  • GC81542 structure
    GC815427-O-Galloyl-D-sedoheptulose
    CAS: 233690-85-2
    Purity: >98%

    7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound.

  • GC81761 structure
    GC817614-Methoxycinnamic acid ethyl ester
    CAS: 1929-30-2
    Purity: >98.50%

    4-Methoxycinnamic acid ethyl ester (Ethyl p-methoxycinnamate) is an orally active natural compound found.

  • GC90889 structure
    GC908895-(3'-Hydroxyphenyl)-γ-Valerolactone
    CAS: 21618-91-7
    Purity: >95.00%

    Un metabolito de varios polifenoles.

  • GC91680 structure
    GC916804-Acetamido Antipyrine
    CAS: 83-15-8
    Purity: >95.00%

    4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .

  • GC91681 structure
    GC91681Loxoprofen-SRS
    CAS: 83648-76-4
    Purity: >98.00%

    Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .

  • GN10004 structure
    GN10004EsculentosideA
    CAS: 65497-07-6
    Purity: >99.50%