Apoptosis
Research Areas
Products Related to Apoptosis(675)
- GC40121(Z-DEVD)2-Rh 110 (trifluoroacetate salt)Purity: >95.00%
(Z-DEVD)2-Rh 110 is a fluorogenic substrate for caspase-3.
- GC40122Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)Purity: >95.00%
Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF.
- GC40123Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt)Purity: >95.00%
Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF.
- GC40125Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt)Purity: >95.00%
Z-VA-DL-D(OMe)-FMK (Z-VAD-FMK) is a pan-caspase inhibitor.
- GC40149Boc-AEVD-CHO (trifluoroacetate salt)Purity: >95.00%
Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively).
- GC40150Z-VEID-AFC (trifluoroacetate salt)Purity: >95.00%
Z-VEID-AFC is a fluorogenic substrate for caspase-6.
- GC40152Ac-IEPD-pNA (trifluoroacetate salt)Purity: >95.00%
Ac-IEPD-pNA is a colorimetric substrate for granzyme B and caspase-8.
- GC40154Ac-ESMD-CHO (trifluoroacetate salt)Purity: >95.00%
Ac-ESMD-CHO is an inhibitor of caspase-3 maturation.
- GC40155Biotin-DEVD-CHO (trifluoroacetate salt)Purity: >95.00%
Biotin-DEVD-CHO is a biotin-conjugated form of the caspase-3 and -7 inhibitor Ac-DEVD-CHO.
- GC40164Ac-IETD-CHO (trifluoroacetate salt)Purity: >95.00%
Ac-IETD-CHO (trifluoroacetate salt) is a caspase 8 inhibitor that can prevent the focal adhesion kinase (Fak) from being cleaved by caspase, with an IC 50 value of 200nM.
- GC40218(-)-Epigallocatechin Gallate-d3/d4Purity: >99.00%
(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS.
- GC40222Lapatinib-d4 (tosylate)CAS: 2749856-05-9Purity: >99.00%
Lapatinib-d4 is intended for use as an internal standard for the quantification of lapatinib by GC- or LC-MS.
- GC4045215(S)-HETE MaxSpec® StandardCAS: 54845-95-3Purity: >98.00%
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
- GC40751Dihydroartemisinic AcidCAS: 85031-59-0Purity: >98.00%
Dihydroartemisinic acid is a biosynthetic precursor to the antimalarial agent artemisinin and an intermediate in the synthesis of artemisinin from artemisinic acid .
- GC40758Gly-Phe-β-naphthylamideCAS: 21438-66-4Purity: >98.00%
Gly-Phe-β-naftilamida es el sustrato de la catepsina C.
- GC41698(D)2-Rh 110 (trifluoroacetate salt)Purity: >95.00%
(D)2-Rh 110 is a fluorogenic caspase substrate.
- GC41742(Z-IETD)2-Rh 110 (trifluoroacetate salt)Purity: >95.00%
(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8.
- GC422403,6-dichloro-benzo[b]thiophene-2-Carboxylic AcidCAS: 34576-94-8Purity: >95.00%
3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 μM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1.
- GC42687Ac-DMQD-AMC (trifluoroacetate salt)Purity: >95.00%
Ac-DMQD-AMC is a fluorogenic substrate for caspase-3.
- GC42688Ac-DMQD-CHO (trifluoroacetate salt)Purity: >95.00%
Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM).
- GC42708Ac-LEHD-AFC (trifluoroacetate salt)Purity: >95.00%
Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC40121 | (Z-DEVD)2-Rh 110 (trifluoroacetate salt) | - | >95.00% | |
(Z-DEVD)2-Rh 110 is a fluorogenic substrate for caspase-3. | ||||
| GC40122 | Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) | - | >95.00% | |
Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. | ||||
| GC40123 | Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt) | - | >95.00% | |
Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF. | ||||
| GC40125 | Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt) | - | >95.00% | |
Z-VA-DL-D(OMe)-FMK (Z-VAD-FMK) is a pan-caspase inhibitor. | ||||
| GC40149 | Boc-AEVD-CHO (trifluoroacetate salt) | - | >95.00% | |
Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively). | ||||
| GC40150 | Z-VEID-AFC (trifluoroacetate salt) | - | >95.00% | |
Z-VEID-AFC is a fluorogenic substrate for caspase-6. | ||||
| GC40152 | Ac-IEPD-pNA (trifluoroacetate salt) | - | >95.00% | |
Ac-IEPD-pNA is a colorimetric substrate for granzyme B and caspase-8. | ||||
| GC40154 | Ac-ESMD-CHO (trifluoroacetate salt) | - | >95.00% | |
Ac-ESMD-CHO is an inhibitor of caspase-3 maturation. | ||||
| GC40155 | Biotin-DEVD-CHO (trifluoroacetate salt) | - | >95.00% | |
Biotin-DEVD-CHO is a biotin-conjugated form of the caspase-3 and -7 inhibitor Ac-DEVD-CHO. | ||||
| GC40162 | Ac-VEID-pNA (trifluoroacetate salt) | - | >95.00% | |
Ac-VEID-pNA is a substrate for caspase-6. | ||||
| GC40164 | Ac-IETD-CHO (trifluoroacetate salt) | - | >95.00% | |
Ac-IETD-CHO (trifluoroacetate salt) is a caspase 8 inhibitor that can prevent the focal adhesion kinase (Fak) from being cleaved by caspase, with an IC 50 value of 200nM. | ||||
| GC40218 | (-)-Epigallocatechin Gallate-d3/d4 | - | >99.00% | |
(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS. | ||||
| GC40222 | Lapatinib-d4 (tosylate) | 2749856-05-9 | >99.00% | |
Lapatinib-d4 is intended for use as an internal standard for the quantification of lapatinib by GC- or LC-MS. | ||||
| GC40452 | 15(S)-HETE MaxSpec® Standard | 54845-95-3 | >98.00% | |
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. | ||||
| GC40751 | Dihydroartemisinic Acid | 85031-59-0 | >98.00% | |
Dihydroartemisinic acid is a biosynthetic precursor to the antimalarial agent artemisinin and an intermediate in the synthesis of artemisinin from artemisinic acid . | ||||
| GC40758 | Gly-Phe-β-naphthylamide | 21438-66-4 | >98.00% | |
Gly-Phe-β-naftilamida es el sustrato de la catepsina C. | ||||
| GC41698 | (D)2-Rh 110 (trifluoroacetate salt) | - | >95.00% | |
(D)2-Rh 110 is a fluorogenic caspase substrate. | ||||
| GC41742 | (Z-IETD)2-Rh 110 (trifluoroacetate salt) | - | >95.00% | |
(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8. | ||||
| GC42240 | 3,6-dichloro-benzo[b]thiophene-2-Carboxylic Acid | 34576-94-8 | >95.00% | |
3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 μM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1. | ||||
| GC42677 | ABO (hydrochloride) | 2309172-24-3 | >95.00% | |
ABO is a modulator of annexin A7. | ||||
| GC42687 | Ac-DMQD-AMC (trifluoroacetate salt) | - | >95.00% | |
Ac-DMQD-AMC is a fluorogenic substrate for caspase-3. | ||||
| GC42688 | Ac-DMQD-CHO (trifluoroacetate salt) | - | >95.00% | |
Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). | ||||
| GC42708 | Ac-LEHD-AFC (trifluoroacetate salt) | - | >95.00% | |
Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9. | ||||
| GC42709 | Ac-LEVD-CHO (trifluoroacetate salt) | - | >95.00% | |
Ac-LEVD-CHO is a caspase-4 inhibitor. | ||||