Innate Immunity

17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain.

Cicaprost (ZK 96480) es un agonista del receptor de prostaciclina (IP).

17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM).

Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.

Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties.

(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide.

1-Stearoyl-2-hydroxy-sn-glycero-3-PC es una forma saturada de lisofosfatidilcolina (Lyso-PC)

N-Linoleoyl phenylalanine is an endogenous N-acyl amine found in D.

Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils.

PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response.

Hecogenin is a natural steroid sapogenin with diverse biological activities that was originally isolated from A.

α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities.

El éster etÍlico del Ácido linoleico inhibe el desarrollo de lesiones aterosclerÓticas y la expresiÓn de mediadores inflamatorios.

Matairesinol confiere efectos antialérgicos en un modelo de ratÓn con dermatitis alérgica.

CAY10591 es un potente activador de Sirt1 y suprime TNF-α de manera dependiente de la dosis.

Sappanone A es una homoisoflavanona con fuertes actividades antiocidantes y anti-inflamatorias.

TSI-01 es un inhibidor selectivo de la lisofosfatidilcolina aciltransferasa 2 (LPCAT2) con valores de IC50 de 0.47 y 3.02 μM para LPCAT2 y LPCAT1 humanos, respectivamente.

(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).

Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria.

(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro).

1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position.

11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA.

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.