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Inicio >> Signaling Pathways >> Immunology/Inflammation >> Innate Immunity

Innate Immunity

Products for  Innate Immunity

  1. Cat.No. Nombre del producto Información
  2. GC18602 p38 MAPK Inhibitor IV p38 MAPK Inhibitor IV es un p38α altamente especÍfico competitivo con ATP; inhibidor de MAPK con IC50 de 0,13 y 0,55 μ M para p38α y p38β MAPK, respectivamente. p38 MAPK Inhibitor IV Chemical Structure
  3. GC52342 P4pal10 (trifluoroacetate salt) A PAR4 and FPR2 antagonist and an FFAR2 agonist P4pal10 (trifluoroacetate salt) Chemical Structure
  4. GC44540 PAF C-16 Carboxylic Acid PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. PAF C-16 Carboxylic Acid Chemical Structure
  5. GC47855 PAF C-16-d4 An internal standard for the quantification of PAF C16 PAF C-16-d4 Chemical Structure
  6. GC44541 PAF C-18 PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. PAF C-18 Chemical Structure
  7. GC41450 PAF C-18:1 PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. PAF C-18:1 Chemical Structure
  8. GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  9. GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  10. GC49061 Pam2CSK4 (trifluoroacetate salt) A bacterial lipopeptide and TLR2 agonist Pam2CSK4 (trifluoroacetate salt) Chemical Structure
  11. GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt) A peptide agonist of PAR2 PAR2 (1-6) amide (human) (trifluoroacetate salt) Chemical Structure
  12. GC44579 PCTR1 PCTR1 es un potente agonista de monocitos/macrÓfagos que regula los procesos antiinflamatorios y pro-resoluciÓn clave durante la infecciÓn bacteriana. PCTR1 Chemical Structure
  13. GC44580 PCTR2 Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR2 Chemical Structure
  14. GC44581 PCTR3 Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR3 Chemical Structure
  15. GC47931 PDE4B Inhibitor A PDE4B inhibitor PDE4B Inhibitor Chemical Structure
  16. GC44590 Pellitorine La pellitorina es un compuesto aislado de las raÍces de Piper nigrum. La pellitorina muestra fuertes actividades citotÓxicas contra las lÍneas celulares HL60 y MCT-7. La pellitorina tiene potencial para la investigaciÓn de enfermedades cancerosas. Pellitorine Chemical Structure
  17. GC52127 Pexiganan (acetate) Pexiganan (acetate) Chemical Structure
  18. GC44633 Phosphatidylserines (bovine) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (bovine) Chemical Structure
  19. GC18522 Phosphatidylserines (sodium salt) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (sodium salt) Chemical Structure
  20. GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor PKI (14-22) amide (myristoylated) (trifluoroacetate salt) Chemical Structure
  21. GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor Plerixafor-d4 Chemical Structure
  22. GC47964 pNPS-DHA An anti-allergic DHEA derivative pNPS-DHA Chemical Structure
  23. GC52270 Pranoprofen-13C-d3 An internal standard for the quantification of pranoprofen Pranoprofen-13C-d3 Chemical Structure
  24. GC48501 Preterramide C La preterramida C es un metabolito fÚngico. Preterramide C Chemical Structure
  25. GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. Prostaglandin D2 methyl ester Chemical Structure
  26. GC47988 Prostaglandin D2-d4 An internal standard for the quantification of prostaglandin D2 Prostaglandin D2-d4 Chemical Structure
  27. GC40981 Protectin D1 Protectin D1, neuroprotectina D1 cuando es generada por células neurales, es miembro de una nueva familia de productos bioactivos generados a partir del Ácido docosahexaenoico. Protectin D1 Chemical Structure
  28. GC48993 Protectin D1-d5 An internal standard for the quantification of protectin D1 Protectin D1-d5 Chemical Structure
  29. GC44794 Pyrrophenone La pirrofenona es un inhibidor potente y especÍfico de la fosfolipasa A2α citosÓlica (cPLA2α) con un valor IC50 de 4,2 nM. Pyrrophenone Chemical Structure
  30. GC40004 Quinolactacin A La quinolactacina A es un inhibidor de la producciÓn de TNF. Quinolactacin A Chemical Structure
  31. GC44802 R-8507 R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI). R-8507 Chemical Structure
  32. GC48461 rac-trans-4-hydroxy Glyburide An active metabolite of glyburide rac-trans-4-hydroxy Glyburide Chemical Structure
  33. GC48035 RCTR1 A specialized pro-resolving mediator RCTR1 Chemical Structure
  34. GC41231 Resolvin D2 methyl ester Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. Resolvin D2 methyl ester Chemical Structure
  35. GC49279 Resolvin D2 n-3 DPA A specialized pro-resolving mediator Resolvin D2 n-3 DPA Chemical Structure
  36. GC48042 Resolvin D2-d5 An internal standard for the quantification of RvD2 Resolvin D2-d5 Chemical Structure
  37. GC41232 Resolvin D3 methyl ester Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. Resolvin D3 methyl ester Chemical Structure
  38. GC44818 Resolvin D4

    Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.

     Resolvin D4 Chemical Structure
  39. GC40982 Resolvin D5

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

     Resolvin D5 Chemical Structure
  40. GC48972 Resolvin E2 A specialized pro-resolving mediator Resolvin E2 Chemical Structure
  41. GC48045 Resolvin E4 A specialized pro-resolving mediator Resolvin E4 Chemical Structure
  42. GC44820 Resveratrol-3-O-Sulfate (sodium salt) El resveratrol-3-O-sulfato (sodio) es el metabolito del resveratrol. Resveratrol-3-O-Sulfate (sodium salt) Chemical Structure
  43. GC41189 Ricinelaidic Acid Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes). Ricinelaidic Acid Chemical Structure
  44. GC44839 Ridaifen-B An analog of tamoxifen Ridaifen-B Chemical Structure
  45. GC48048 Rifampicin-d3 An internal standard for the quantification of rifampicin Rifampicin-d3 Chemical Structure
  46. GC44851 Rosiglitazone (potassium salt) La rosiglitazona (BRL 49653) potÁsica es un PPARγ selectivo activo por vÍa oral; agonista (EC50: 60 nM, Kd: 40 nM). Rosiglitazone (potassium salt) Chemical Structure
  47. GC48059 Rosiglitazone-d3 An internal standard for the quantification of rosiglitazone Rosiglitazone-d3 Chemical Structure
  48. GC41626 Sappanone A

    La sappanona A es una homoisoflavano con fuertes actividades antioxidantes y antiinflamatorias.

     Sappanone A Chemical Structure
  49. GC46221 Seselin An angular pyranocoumarin with diverse biological activities Seselin Chemical Structure
  50. GC18821 SGA360 SGA360 suprime la seÑalizaciÓn inflamatoria de SAA1 de una manera dependiente de AHR a través de un mecanismo que no requiere la uniÓn de AHR a su elemento de respuesta afÍn (antagonista parcial) . SGA360 Chemical Structure
  51. GC49333 SH-42

    Un inhibidor de DHCR24.

     SH-42 Chemical Structure
  52. GC49002 Sinigrin (hydrate) Sinigrin (hidrato) es un glucosinolato alifático natural presente en plantas de la familia Brassicaceae. Sinigrin (hydrate) Chemical Structure
  53. GC49049 SMU127 An agonist of TLR1/2 SMU127 Chemical Structure
  54. GC49400 SN-011 SN-011 es un inhibidor de STING humano y de ratÓn potente y selectivo, con una IC50 de 76 nM para la seÑalizaciÓn de STING. SN-011 Chemical Structure
  55. GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) Chemical Structure
  56. GC44919 SP 600125, negative control SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM. SP 600125, negative control Chemical Structure
  57. GC44930 Sphingosine (d14:1) La esfingosina (d14:1) (Tetradecasphing-4-enine), un esfingolÍpido, es un potente inhibidor de la proteÍna quinasa C (PKC). La esfingosina (d14:1) evita su interacciÓn con ésteres de sn-1,2-diacilglicerol (DAG)/forbol. Sphingosine (d14:1) Chemical Structure
  58. GC48098 SR 12343 An IKKβ NBD mimetic SR 12343 Chemical Structure
  59. GC48099 SR 12460 An IKKβ NBD mimetic SR 12460 Chemical Structure
  60. GC45567 SR 1903   SR 1903 Chemical Structure
  61. GC61293 SR-717 SR-717 es un agonista de STING sin nucleÓtidos con EC50 de 2,1 μM y 2,2 μM en las lÍneas celulares ISG-THP1 (WT) e ISG-THP1 cGAS KO (cGAS KO), respectivamente. SR-717 Chemical Structure
  62. GC45831 SRI-011381 SRI-011381 es un agonista de seÑalizaciÓn de TGF-β activo por vÍa oral, exhibe efectos neuroprotectores. SRI-011381 Chemical Structure
  63. GC40922 SRS11-92 SRS11-92, un anÁlogo de Ferrostatin-1 (Fer-1), es un potente inhibidor de la ferroptosis. SRS11-92 Chemical Structure
  64. GC44948 StA-IFN-1 StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway. StA-IFN-1 Chemical Structure
  65. GC49844 Stercobilin (hydrochloride) A fecal pigment and metabolite of bilirubin Stercobilin (hydrochloride) Chemical Structure
  66. GC48109 STING Agonist 12b A STING agonist STING Agonist 12b Chemical Structure
  67. GC48110 STING Agonist 1a STING Agonist 1a (1a) es un estimulador especÍfico de los genes de interferÓn (STING) agonista. STING Agonist 1a Chemical Structure
  68. GC45570 STING Agonist C11   STING Agonist C11 Chemical Structure
  69. GC46227 STING18 A competitive STING ligand STING18 Chemical Structure
  70. GC44956 Streptochlorin Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. Streptochlorin Chemical Structure
  71. GC52496 Sulfatide (bovine) (sodium salt) A mixture of isolated bovine sulfatides Sulfatide (bovine) (sodium salt) Chemical Structure
  72. GC44968 Sulfatides (bovine) (sodium salt) Sulfatides are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system. Sulfatides (bovine) (sodium salt) Chemical Structure
  73. GC18453 Sulochrin

    Sulochrina es un metabolito fúngico producido por A.

     Sulochrin Chemical Structure
  74. GC48764 Sydowinin B A xanthone polyketide with immunosuppressant activity Sydowinin B Chemical Structure
  75. GC49047 T-5342126 A TLR4 antagonist T-5342126 Chemical Structure
  76. GC48447 TAS 205 An inhibitor of H-PGDS TAS 205 Chemical Structure
  77. GC44999 Tauro-α-muricholic Acid (sodium salt) Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid. Tauro-α-muricholic Acid (sodium salt) Chemical Structure
  78. GC45004 TC 14012 (trifluoroacetate salt) C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12). TC 14012 (trifluoroacetate salt) Chemical Structure
  79. GC49105 Tebipenem (hydrate) A carbenapenem antibiotic Tebipenem (hydrate) Chemical Structure
  80. GC45012 Tenofovir diphosphate (sodium salt) Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). Tenofovir diphosphate (sodium salt) Chemical Structure
  81. GC49386 Tepoxalin La tepoxalina es un inhibidor dual de la COX y la 5-lipoxigenasa (5-LO) con una potente actividad antiinflamatoria y un perfil gastrointestinal favorable. Tepoxalin Chemical Structure
  82. GC40627 tetranor-Misoprostol tetranor-Misoprostol is a metabolite of misoprostol. tetranor-Misoprostol Chemical Structure
  83. GC19001 Tetromycin B Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively. Tetromycin B Chemical Structure
  84. GC45030 TG6-129 TG6-129 es un antagonista selectivo del receptor EP2. TG6-129 Chemical Structure
  85. GC48163 Theophylline-d6 La teofilina-d6 (1,3-dimetilxantina-d6) es la teofilina marcada con deuterio. La teofilina es un inhibidor no selectivo de la fosfodiesterasa (PDE), un bloqueador del receptor de adenosina y un activador de la histona desacetilasa (HDAC). Theophylline-d6 Chemical Structure
  86. GC49503 Thujopsene A sesquiterpene with diverse biological activities Thujopsene Chemical Structure
  87. GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) Chemical Structure
  88. GC49062 Tiopronin-d3 Tiopronin-d3 es el Tiopronin marcado con deuterio. Tiopronin-d3 Chemical Structure
  89. GC45057 TIQ-A TIQ-A es un potente inhibidor de TNKS (poli-ART, PARP), con una IC50 de 24 nM para TNKS2. TIQ-A Chemical Structure
  90. GC45965 Tolfenamic Acid-d4 An internal standard for the quantification of tolfenamic acid Tolfenamic Acid-d4 Chemical Structure
  91. GC45063 Toll-Like Receptor 7 Ligand II Toll-Like Receptor 7 Ligand II (CL-087) es un potente agonista oral activo de TLR7. Toll-Like Receptor 7 Ligand II Chemical Structure
  92. GC49150 Tpl2 Kinase Inhibitor (hydrochloride) A Tpl2 inhibitor Tpl2 Kinase Inhibitor (hydrochloride) Chemical Structure
  93. GC48202 Treprostinil (diethanolamine salt) Treprostinil (UT-15C) dietanolamina es un potente agonista de EP2, DP1 e IP con valores de Ki de 3,6, 4,4, 32,1, 212, 826, 2505 y 4680 nM para EP2, DP1, IP, EP1, EP4, EP3 y FP, respectivamente . Treprostinil (diethanolamine salt) Chemical Structure
  94. GC49685 Trifluoroacetyl Tripeptide-2 (acetate) A peptide inhibitor of pancreatic and neutrophil elastases Trifluoroacetyl Tripeptide-2 (acetate) Chemical Structure
  95. GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline Trigonelline-d3 (chloride) Chemical Structure
  96. GC41638 TSI-01

    El factor activador de plaquetas (PAF) es un mediador proinflamatorio de fosfolípidos que se sintetiza rápidamente por la lisofosfatidilcolina acetiltransferasa (lyso-PAFAT) en respuesta a estímulos extracelulares.

     TSI-01 Chemical Structure
  97. GC52412 TT-232 (trifluoroacetate salt) A synthetic peptide derivative of somatostatin TT-232 (trifluoroacetate salt) Chemical Structure
  98. GC49099 Tuftsin (human) (trifluoroacetate salt) A phagocytosis-stimulating peptide Tuftsin (human) (trifluoroacetate salt) Chemical Structure
  99. GC49835 Tumulosic Acid El Ácido tumulÓsico, un triterpenoide, inhibe la actividad de la proteasa KLK5 (IC50= 14,84 μM). Tumulosic Acid Chemical Structure
  100. GC48987 UDP (sodium salt hydrate) An agonist of P2Y6 UDP (sodium salt hydrate) Chemical Structure
  101. GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide Vimentin (139-159)-biotin Peptide Chemical Structure

Artículos 301 al 400 de 407 totales

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