Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC49372Kaempferol 7-neohesperidosideCAS: 17353-03-6Purity: >95.00%
A flavonoid glycoside with antioxidant and anticancer activities
- GC49420Gallic Acid-d2CAS: 294660-92-7Purity: >99.00%
An internal standard for the quantification of gallic acid
- GC49422PAR2 (1-6) amide (human) (trifluoroacetate salt)CAS: 2379569-17-0Purity: >95.00%
A peptide agonist of PAR2
- GC49426Taurine-d4CAS: 342611-14-7Purity: >99.00%
An internal standard for the quantification of taurine
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8Purity: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8Purity: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
- GC52027IsolariciresinolCAS: 548-29-8Purity: >98.00%
El isolariciresinol ((+)-Cyclolariciresinol) se puede utilizar para la investigación de la reumatitis.
- GC52073N-formyl-2-AminophenolCAS: 2843-27-8Purity: >98.00%
A bacterial secondary metabolite with antioxidant activity
- GC52081ChamazuleneCAS: 529-05-5Purity: >98.00%
El chamazuleno, un compuesto natural, es un inhibidor de tipo antioxidante de la formaciÓn de leucotrieno B4.
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9Purity: >98.00%
Imidazole Ketone Erastin es un inhibidor de xc e inductor de ferroptosis eficaz y metabólicamente estable.
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8Purity: >95.00%
An active metabolite of various polyphenols
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49372 | Kaempferol 7-neohesperidoside | 17353-03-6 | >95.00% | |
A flavonoid glycoside with antioxidant and anticancer activities | ||||
| GC49420 | Gallic Acid-d2 | 294660-92-7 | >99.00% | |
An internal standard for the quantification of gallic acid | ||||
| GC49422 | PAR2 (1-6) amide (human) (trifluoroacetate salt) | 2379569-17-0 | >95.00% | |
A peptide agonist of PAR2 | ||||
| GC49426 | Taurine-d4 | 342611-14-7 | >99.00% | |
An internal standard for the quantification of taurine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49500 | Stobadine | 85202-17-1 | >98.00% | |
A pyridoindole antioxidant | ||||
| GC49521 | MHY553 | 6265-56-1 | >98.00% | |
An agonist of PPARα | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49560 | L6H21 | 24533-47-9 | >98.00% | |
L6H21, un derivado de la chalcona, es un inhibidor de la diferenciaciÓn mieloide 2 (MD-2) activo, potente y especÍfico por vÍa oral. | ||||
| GC49597 | Leukotriene B4-d5 | - | >99.00% | |
An internal standard for the quantification of LTB 4 | ||||
| GC49708 | Biliverdin (technical grade) | 114-25-0 | >70.00% | |
A bile pigment | ||||
| GC49790 | Reuterin | 2134-29-4 | >98.00% | |
La reuterina es un agente antimicrobiano de amplio espectro activo contra bacterias Gram positivas y Gram negativas, asÍ como levaduras, mohos y protozoos. | ||||
| GC49849 | 3-Aminosalicylic Acid | 570-23-0 | >98.00% | |
A salicylic acid derivative | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49864 | 6-Methylpterin | 708-75-8 | >98.00% | |
A derivative of folic acid | ||||
| GC49868 | D-α-Tocopheryl Quinone | 7559-04-8 | >98.00% | |
An oxidative metabolite of vitamin E | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
El isolariciresinol ((+)-Cyclolariciresinol) se puede utilizar para la investigación de la reumatitis. | ||||
| GC52073 | N-formyl-2-Aminophenol | 2843-27-8 | >98.00% | |
A bacterial secondary metabolite with antioxidant activity | ||||
| GC52081 | Chamazulene | 529-05-5 | >98.00% | |
El chamazuleno, un compuesto natural, es un inhibidor de tipo antioxidante de la formaciÓn de leucotrieno B4. | ||||
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
Cu-ATSP, un potente inhibidor de la muerte celular ferroptótica, es casi 20 veces más potente que CuATSM. | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin es un inhibidor de xc e inductor de ferroptosis eficaz y metabólicamente estable. | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||