RFRP-1 (human) |
| Catalog No.GC50232 |
RFRP-1 (humano) es un homólogo de la hormona inhibidora de la gonadotropina (GnIH).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 311309-25-8
Sample solution is provided at 25 µL, 10mM.
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Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.
Gouardères et al (2006) Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPγS binding. Neuropharmacology 52 376 PMID:17011599 |Nichols et al (2010) Human RFamide-related peptide-1 diminishes cellular and integrated cardiac contractile performance. Peptides 31 2067 PMID:20797420 |Hinuma et al (2000) New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat.Cell.Biol. 2 703 PMID:11025660
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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