GLPBio

Tat-IKIP (46-60) TFA

Catalog No.: GC79811Purity:>99.50%
COASDSData Sheet
Tat-IKIP (46-60) TFA is the trifluoroacetic acid of Tat-IKIP (46-60).

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.

Tat-IKIP (46-60) TFA
1mgIn Stock
$90.00
1
5mgIn Stock
$306.00
1
10mgIn Stock
$432.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Descripción (Description)

Tat-IKIP (46-60) TFA is the trifluoroacetic acid of Tat-IKIP (46-60). Tat-IKIP (46-60) is a IκB kinase ( IKK ) -targeting membrane-penetrating peptide. Tat-IKIP (46-60) inhibits IKK activation and NF-κB targeted gene expression by disrupting the IKKβ/NEMO complex. Tat-IKIP (46-60) significantly reduces DSS -induced acute inflammation in inflammatory bowel disease (IBD) mice model and attenuates Zymosan-induced acute arthritis in acute arthritis model (AAM). Tat-IKIP (46-60) can be used for inflammatory diseases research, such as IBD, pancreatitis and rheumatoid arthritis [1] [2].

References:
[1]. Liu H, et al. A Peptide Derived from IKK-Interacting Protein Attenuates NF-κB Activation and Inflammation. J Immunol. 2021 Sep 15;207(6):1652-1661.
[2]. Gao, C.J, et al. IKK beta-targeting short peptides and application thereof in inflammatory diseases. 2020-11-24.

Documentos del producto (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

Fórmula molecular
C145H246N48O31S·xC2HF3O2
Peso molecular
3189.87
Solubilidad
DMSO: 100 mg/mL (Need ultrasonic)
Almacenamiento
Sealed storage, away from moisture
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

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