Thymopentin acetate (Synonyms: RKDVY, Thymopoietin II (32-36), Thymopoietin Pentapeptide, TP5) |
Catalog No.GC39199
One-Click Copy Product Info
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El acetato de timopentina es un péptido biolÓgicamente activo secretado principalmente por las células epiteliales de la corteza y la médula del timo.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 89318-88-7
Sample solution is provided at 25 µL, 10mM.
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Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs)[1][2].
[1]. Zhu MX, et al. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells in vitro. Exp Cell Res. 2015 Feb 15;331(2):387-98. [2]. Lin S, et al. Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology. Eur J Pharm Biopharm. 2018 Jan;122:104-112.
| Cas No. | 89318-88-7 | SDF | |
| Sinónimos | RKDVY, Thymopoietin II (32-36), Thymopoietin Pentapeptide, TP5 | ||
| Formula | C32H53N9O11 | M.Wt | 739.82 |
| Solubility | H2O : 25 mg/mL (33.79 mM; ultrasonic and heat to 60°C); DMSO : 25 mg/mL (33.79 mM; Need ultrasonic) | Storage | -20°C, away from moisture and light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.3517 mL | 6.7584 mL | 13.5168 mL |
| 5 mM | 270.3 μL | 1.3517 mL | 2.7034 mL |
| 10 mM | 135.2 μL | 675.8 μL | 1.3517 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.50% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)