SRPK
SRPK (serine/arginine-rich protein-specific kinases) specifically phosphorylate their substrate at serine residues in RS domain. It functions in SR splicing factors phosphorylation and splicing regulation. It is involvd in regulation of HBV replication, neuronal apoptosis and muscle development etc.
Products Related to SRPK(6)
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC13596 | SRPIN340 | 218156-96-8 | >99.50% | |
Selective SRPK1 inhibitor | ||||
| GC19456 | SPHINX31 | 1818389-84-2 | >98.00% | |
A potent inhibitor of SRPK1 | ||||
| GC32583 | SRPKIN-1 | 2089226-94-6 | >98.00% | |
SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. | ||||
| GC65981 | SPHINX | 848057-98-7 | >99.00% | |
SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD. | ||||
| GC69507 | MSC-1186 | 2871698-23-4 | >99.00% | |
MSC-1186 is a highly selective pan-SRPK inhibitor. It has activity against SRPK1, SRPK2, and SRPK3 with IC50 values of 2.7 nM, 81 nM, and 0.6 nM respectively. MSC-1186 can be used for cancer research. | ||||
| GC72856 | SRPIN803 | 380572-02-1 | >99.00% | |
SRPIN803 is a potent CK2 and SRPK1 dual inhibitor, with IC50s of 203 nM and 2.4 μM, respectively. | ||||