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SPHINX31

Catalog No.GC19456

A potent inhibitor of SRPK1

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SPHINX31 Chemical Structure

Cas No.: 1818389-84-2

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5mg
$83.00
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10mg
$111.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].

References:
[1]. Batson J, et al. Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease. ACS Chem Biol. 2017 Mar 17;12(3):825-832.

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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