STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC 50 of 2 nM. STAT6-IN-10 can inhibit the secretion of CCL17 in human peripheral whole blood. STAT6-IN-10 can be used in the research of dermatological and respiratory system diseases [1].
In Vitro, STAT6-IN-10 (Example 10) can inhibit the secretion of CCL17 in human peripheral whole blood, and its IC50 is 0.095 μM[1].
References:
[1]. Chulho Cho, et al. Nitrogen-containing heteroaryl compounds for the treatment of chronic disease. WO2025133961. 2025-06-26.
In Vitro, STAT6-IN-10 (Example 10) can inhibit the secretion of CCL17 in human peripheral whole blood, and its IC50 is 0.095 μM[1].
References:
[1]. Chulho Cho, et al. Nitrogen-containing heteroaryl compounds for the treatment of chronic disease. WO2025133961. 2025-06-26.
















