GLPBio

STAT6-IN-10

Catalog No.: GC79469Purity:>98.50%
STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC 50 of 2 nM.

Products are for research use only. Not for human use. We do not sell to patients.


STAT6-IN-10
Cas No.: 3092076-19-9
10mM (in 1mL DMSO)In Stock
$629.00
1
1mgIn Stock
$225.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC 50 of 2 nM. STAT6-IN-10 can inhibit the secretion of CCL17 in human peripheral whole blood. STAT6-IN-10 can be used in the research of dermatological and respiratory system diseases [1].

In Vitro, STAT6-IN-10 (Example 10) can inhibit the secretion of CCL17 in human peripheral whole blood, and its IC50 is 0.095 μM[1].

References:
[1]. Chulho Cho, et al. Nitrogen-containing heteroaryl compounds for the treatment of chronic disease. WO2025133961. 2025-06-26.

Product Documents

Purity:>98.50%Appearance:A solid

Chemical Properties

CAS No.
3092076-19-9
Molecular Formula
C29H29N7O2
Molecular Weight
507.59
Solubility
DMSO: 25 mg/mL (49.25 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

Review for STAT6-IN-10

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%