GLPBio

SYY-B029-2

Catalog No.: GC79156Purity:>99.50%
SYY-B029-2 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 of 1.4 nM.

Products are for research use only. Not for human use. We do not sell to patients.


SYY-B029-2
Cas No.: 2379410-19-0
10mM (in 1mL DMSO)In Stock
$1,624.00
1
1mgIn Stock
$540.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

SYY-B029-2 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 of 1.4 nM. SYY-B029-2 cell growth of human mantle cell lymphoma (MCL) cell line MAVER-1 and human castration resistant prostate cancer cell line LNCaP clone FGC, with IC50 values of 15 nM and 13 nM, respectively [1].

References:
[1]. Bing Zhou, et al. Histone acetyltransferase (hat) inhibitor and use thereof. WO2019201291A1.

Product Documents

Purity:>99.50%Appearance:A solid

Chemical Properties

CAS No.
2379410-19-0
Molecular Formula
C27H27FN4O6
Molecular Weight
522.52
Solubility
DMSO: ≥ 100 mg/mL (191.38 mM)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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