TMP780 |
| Catalog No.GC62520 |
TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1422053-03-9
Sample solution is provided at 25 µL, 10mM.
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TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].
[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75.
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