TRV045 is a selective Sphingosine-1-phosphate subtype 1 receptor agonist with no effect on lymphocyte transport. TRV045 has antiepileptic activity [1].
References:
[1]. de Cuba CMKE, et al. TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects. Clin Pharmacol Ther. 2024 Dec 6.
References:
[1]. de Cuba CMKE, et al. TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects. Clin Pharmacol Ther. 2024 Dec 6.
















