GLPBio

UCCF-853

Catalog No.: GC72897Purity:>99.00%
UCCF-853 is a CFTR modulator.

Products are for research use only. Not for human use. We do not sell to patients.


UCCF-853
Cas No.: 625458-06-2
5 mgIn Stock
$81.00
1
10 mgIn Stock
$126.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

UCCF-853 is a CFTR modulator.

References:
[1]. Nicoletta Pedemonte, et al. Influence of cell background on pharmacological rescue of mutant CFTR. Am J Psiol Cell Psiol. 2010 Apr;298(4):C866-74.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
625458-06-2
Molecular Formula
C14H8ClF3N2O
Molecular Weight
312.67
Solubility
DMSO : ≥ 125 mg/mL (399.78 mM)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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