URAT1
URAT1, also known as SLC22A12, is an organic anion and urate transporter. It regulates urate levels of blood and is required for urate reabsorption of kidney.
Products Related to URAT1(14)
- GC36439Lesinurad sodiumCAS: 1151516-14-1Purity: >99.50%
Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 ?M, respectively.
- GC65362URAT1 inhibitor 1CAS: 2268720-62-1Purity: >98%
URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM.
- GC69779PuliginuradCAS: 2013582-27-7Purity: >99.00%
Puliginurad (YL-90148) is an effective inhibitor of urate transporter protein (URAT). Puliginurad can be used in research on hyperuricemia and gout.
- GC71155URAT1 inhibitor 3CAS: 2850331-30-3Purity: >98.00%
URAT1 inhibitor 3 is a potent, orally active, selective URAT1 inhibitor with an IC50 value of 0.8 nM.
- GC71285URAT1&XO inhibitor 1CAS: 2669726-78-5Purity: >99.00%
URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM).
- GC71286URAT1 inhibitor 6CAS: 2244807-49-4
URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1).
- GC71287URAT1 inhibitor 8CAS: 1632005-33-4Purity: >98.00%
URAT1 inhibitor 8 (example 247) is a potent URAT1 inhibitor, with an IC50 of 0.001 μM.
- GC71288URAT1&XO inhibitor 2CAS: 1239488-96-0Purity: >98.00%
URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase.
- GC81725TRPV1 antagonist 10CAS: 896584-55-7Purity: >98.50%
TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist ( IC 50 = 33.06 nM), moderate to weak URAT1 ( IC 50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor.
- GC81738URAT1 inhibitor 7CAS: 1632002-28-8Purity: >98.00%
URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC 50 of 12 nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC15440 | Lesinurad | 878672-00-5 | >98.00% | |
A URAT1 inhibitor | ||||
| GC19373 | Verinurad | 1352792-74-5 | >99.00% | |
Verinurad is an urate transporter inhibitor with EC50 value of 0.05 uM. | ||||
| GC36439 | Lesinurad sodium | 1151516-14-1 | >99.50% | |
Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 ?M, respectively. | ||||
| GC63422 | Ruzinurad | 1638327-48-6 | >99.00% | |
Ruzinurad is a highly selective URATl inhibitor (WO2020088641, compound I). | ||||
| GC65362 | URAT1 inhibitor 1 | 2268720-62-1 | >98% | |
URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. | ||||
| GC69779 | Puliginurad | 2013582-27-7 | >99.00% | |
Puliginurad (YL-90148) is an effective inhibitor of urate transporter protein (URAT). Puliginurad can be used in research on hyperuricemia and gout. | ||||
| GC70152 | Xininurad | 2365178-28-3 | >99.00% | |
Xininurad (XNW3009) is a urate transporter (URAT) inhibitor. | ||||
| GC71155 | URAT1 inhibitor 3 | 2850331-30-3 | >98.00% | |
URAT1 inhibitor 3 is a potent, orally active, selective URAT1 inhibitor with an IC50 value of 0.8 nM. | ||||
| GC71285 | URAT1&XO inhibitor 1 | 2669726-78-5 | >99.00% | |
URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). | ||||
| GC71286 | URAT1 inhibitor 6 | 2244807-49-4 | - | |
URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). | ||||
| GC71287 | URAT1 inhibitor 8 | 1632005-33-4 | >98.00% | |
URAT1 inhibitor 8 (example 247) is a potent URAT1 inhibitor, with an IC50 of 0.001 μM. | ||||
| GC71288 | URAT1&XO inhibitor 2 | 1239488-96-0 | >98.00% | |
URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. | ||||
| GC81725 | TRPV1 antagonist 10 | 896584-55-7 | >98.50% | |
TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist ( IC 50 = 33.06 nM), moderate to weak URAT1 ( IC 50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor. | ||||
| GC81738 | URAT1 inhibitor 7 | 1632002-28-8 | >98.00% | |
URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC 50 of 12 nM. | ||||