USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10)[1].
[1]. Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.
USP8-IN-1
Catalog No.: GC64537Purity:>99.00%
USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2477650-96-5
5 mgIn Stock
$234.00
1
10 mgIn Stock
$342.00
1
25 mgIn Stock
$720.00
1
50 mgIn Stock
$1,152.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5 mg | $234.00 | In Stock | 1 | |
| 10 mg | $342.00 | In Stock | 1 | |
| 25 mg | $720.00 | In Stock | 1 | |
| 50 mg | $1,152.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.00%Appearance:A solid
Chemical Properties
CAS No.
2477650-96-5
Molecular Formula
C18H21N5O3S
Molecular Weight
387.46
Solubility
DMSO : 125 mg/mL (322.61 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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