GLPBio

WWP1/2-IN-1

Catalog No.: GC84415
COASDSData Sheet
WWP1/2-IN-1 (compound 11) is a WWP1/2 inhibitor with the IC50 values of 32.7µM and 269.2µM for WWP1 and WWP2, respectively [1].

Products are for research use only. Not for human use. We do not sell to patients.

WWP1/2-IN-1
10mM (in 1mL DMSO)In Stock
$185.00
1
5mgIn Stock
$168.00
1
10mgIn Stock
$268.00
1
25mgIn Stock
$536.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

WWP1/2-IN-1 (compound 11) is a WWP1/2 inhibitor with the IC50 values of 32.7µM and 269.2µM for WWP1 and WWP2, respectively [1].

References:
[1]. Dudey AP, et al. Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2394895.

Product Documents

Appearance:A solid
COASDSData Sheet

Chemical Properties

Molecular Formula
C11H12Cl2N4O2S
Molecular Weight
335.21
Solubility
DMSO: 100 mg/mL (298.32 mM; Need ultrasonic)
Storage
Store at 4°C, sealed storage, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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