GLPBio

WYneN

Catalog No.: GC92015Purity:>95.00%Synonyms: Wittig-alkyne N
COASDSData Sheet
WYneN is a chemoselective probe for the detection of sulfenylated proteins in live cells.

Products are for research use only. Not for human use. We do not sell to patients.

WYneN
Cas No.: 3052492-38-0
10 mgIn Stock
$139.00
1
25 mgIn Stock
$294.00
1
50 mgIn Stock
$519.00
1
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Description

WYneN is a chemoselective probe for the detection of sulfenylated proteins in live cells.1 It is selective for sulfenylated proteins over 5,5′-dithiobis-(2-nitrobenzoic acid) (DTNB) and 4,4′-dipyridyl disulfide (4-DPS). WYneN binds to sulfenylated proteins in live cells and can then be conjugated to azide-containing fluorescent probes for detection.

References:
[1]. Shi, Y., Fu, L., Yang, J., et al.Wittig reagents for chemoselective sulfenic acid ligation enables global site stoichiometry analysis and redox-controlled mitochondrial targetingNat. Chem.13(11)1140-1150(2021).

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
3052492-38-0
Synonyms
Wittig-alkyne N
Chemical Name
[2-oxo-2-(2-propyn-1-ylamino)ethyl]triphenyl-phosphonium, monobromide
SMILES
O=C(NCC#C)C[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]
Molecular Formula
C23H21NOP ? Br
Molecular Weight
438.3
Solubility
DMSO: Sparingly soluble: 1-10 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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