GLPBio

Z36-MP5

Catalog No.: GC73946Purity:>99.00%
COASDSData Sheet
Z36-MP5 is an Mi-2β-targeted inhibitor, with IC50 of 0.082 μM.

Products are for research use only. Not for human use. We do not sell to patients.

Z36-MP5
Cas No.: 2839660-03-4
10mM (in 1mL DMSO)In Stock
$173.00
1
5 mgIn Stock
$158.00
1
10 mgIn Stock
$252.00
1
25 mgIn Stock
$504.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Z36-MP5 is an Mi-2β-targeted inhibitor, with IC50 of 0.082 μM. Z36-MP5 can reduce Mi-2β ATPase activity and reactivates ISG transcription. Z36-MP5 can stimulate T-cell-mediated cytotoxicity.

References:
[1]. Cang Li, et al. Mi-2β promotes immune evasion in melanoma by activating EZH2 metlation. Nat Commun. 2024 Mar 9;15(1):2163.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2839660-03-4
Molecular Formula
C22H21N5O2
Molecular Weight
387.43
Solubility
DMSO : 25 mg/mL (64.53 mM; ultrasonic and warming and heat to 60°C)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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