GLPBio

ZCL279

Catalog No.: GC84447Purity:>99.00%
COASDSData Sheet
ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction.

Products are for research use only. Not for human use. We do not sell to patients.

ZCL279
Cas No.: 664975-73-9
10mM (in 1mL DMSO)In Stock
$210.00
1
5mgIn Stock
$187.00
1
10mgIn Stock
$297.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction. ZCL279 can activate Cdc42 (a cytoplasmic small GTPase in the Ras superfamily) at lower concentrations (<10 μM) and significantly inhibit it at higher concentrations (<10 μM) [1].

References:
[1]. Malasala S, et al. Enabling Systemic Identification and Functionality Profiling for Cdc42 Homeostatic Modulators. bioRxiv [Preprint]. 2024 Jan 8:2024.01.05.574351.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
664975-73-9
Molecular Formula
C24H18N2O7S2
Molecular Weight
510.54
Solubility
DMSO: 50 mg/mL (97.94 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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