GLPBio

ZEN-3862

Catalog No.: GC84451Purity:>95.00%
COASDSData Sheet
ZEN-3862 is a BET inhibitor with IC50 s of 0.16 and 0.13 μM for BRD4 (BD1) and BRD4 (BD2), respectively.

Products are for research use only. Not for human use. We do not sell to patients.

ZEN-3862
Cas No.: 1952264-33-3
10mM (in 1mL DMSO)In Stock
$91.00
1
1mgIn Stock
$38.00
1
5mgIn Stock
$83.00
1
10mgIn Stock
$126.00
1
25mgIn Stock
$225.00
1
50mgIn Stock
$295.00
1
100mgIn Stock
$404.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

ZEN-3862 is a BET inhibitor with IC50 s of 0.16 and 0.13 μM for BRD4 (BD1) and BRD4 (BD2), respectively. ZEN-3862 can be used to form PROTAC s to induce degradation of BRD4 [1].

References:
[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1952264-33-3
Molecular Formula
C19H17FN2O3
Molecular Weight
340.35
Solubility
DMSO: 83.33 mg/mL (244.84 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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