GLPBio

ZER1 binder-2

Catalog No.: GC79629Purity:>98%
ZER1 binder-2 is a ZER1 E3 ubiquitin ligase binder with an EC 50 value of 51.04 nM.

Products are for research use only. Not for human use. We do not sell to patients.


ZER1 binder-2
Cas No.: 3132618-63-1
1mgIn Stock
$713.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

ZER1 binder-2 is a ZER1 E3 ubiquitin ligase binder with an EC 50 value of 51.04 nM. ZER1 binder-2 is applicable to the research of cancers induced by HPV infection [1].

In Vitro, ZER1 binder-2 (Example 313) binds to the purified ZER1 (469-766) protein in fluorescence polarization assays, with an EC50 of 51.04 nM[1].

References:
[1]. HENDERSON, et al. ZER1 BINDERS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF. WO2026122416. PCT. 11.06.2026.

Chemical Properties

CAS No.
3132618-63-1
Molecular Formula
C18H16ClN7O2
Molecular Weight
397.82
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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