(2R)-RXP470.1 ((2R)-RXP-470) is the (2R)-isomer of RXP470.1. RXP470.1 (RXP-470) is a potent, selective MMP-12 inhibitor with a K i of 0.2 nM against human MMP-12 [1].
References:
[1]. Jason L Johnson, et al. A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):528-35.
References:
[1]. Jason L Johnson, et al. A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):528-35.