4-Chlorochalcone (Compound 3) is a monoamine oxidase inhibitor (hMAO-B: IC50 = 0.082 μM, hMAO-A: IC50 = 9.95 μM). 4-Chlorochalcone also exhibits inhibitory activity against cholinesterase (AChE: IC50 = 2.79 μM). 4-Chlorochalcone is a chalcone derivative [1].
References:
[1]. Oh JM, et al. Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives. Int J Biol Macromol. 2019 Sep 15;137:426-432.
References:
[1]. Oh JM, et al. Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives. Int J Biol Macromol. 2019 Sep 15;137:426-432.
















