ABC1183
Catalog No.: GC68592Purity:>98%
ABC1183 is a selective dual inhibitor of GSK3 and CDK9 with oral activity. Its IC50 values for GSK3β, GSK3α, and CDK9/cyclin T1 are 657 nM, 327 nM, and 321 nM respectively. ABC1183 has anti-inflammatory properties as well as anti-tumor activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1042735-18-1
10 mM * 1mLinDMSOIn Stock
$89.10
1
5mgIn Stock
$81.00
1
10mgIn Stock
$129.60
1
25mgIn Stock
$270.00
1
50mgIn Stock
$432.00
1
100mgIn Stock
$691.20
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10 mM * 1mLinDMSO | $89.10 | In Stock | 1 | |
| 5mg | $81.00 | In Stock | 1 | |
| 10mg | $129.60 | In Stock | 1 | |
| 25mg | $270.00 | In Stock | 1 | |
| 50mg | $432.00 | In Stock | 1 | |
| 100mg | $691.20 | In Stock | 1 |
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com
Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Chemical Properties
CAS No.
1042735-18-1
Molecular Formula
C18H14N4OS
Molecular Weight
334.39
Solubility
DMSO : 125 mg/mL (373.82 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
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