AC 4 |
| Catalog No.GC50169 |
Photoswitchable TRPV1 channel blocker
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1459809-09-6
Sample solution is provided at 25 µL, 10mM.
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Photoswitchable TRPV1 channel blocker (IC50 = 3.1 μM). Acts as an antagonist in trans conformation during voltage gated activation. Also acts as an antagonist in the cis formation during capsaicin-induced TRPV1 currents. Switches conformation from cis to trans at 440 nm and trans to cis at 360 nm. Allows photoswitchable antagonist and an agonist to be applied at the same time.
Stein et al (2013) Optical control of TRPV1 channels. Angew.Chem.Int.Ed.Engl. 52 9845 PMID:23873837
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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