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Angeli’s Salt

Catalog No.: GC19428Purity:>99.00%Synonyms: Sodium α-oxyhyponitrite

A classical nitroxyl (NO-) donor

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Angeli’s Salt
Cas No.: 13826-64-7
5mgIn Stock
$45.00
1
10mgIn Stock
$86.00
1
50mgIn Stock
$349.00
1
100mgIn Stock
$609.00
1

Citations

2 publicationsPublications from researchers using this product

Description

Angeli’s salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37°C (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2]

Reference:
[1]. Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ∙NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects Journal of Medicinal Chemistry 34, 3242-3247 (1991).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996).

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
13826-64-7
Synonyms
Sodium α-oxyhyponitrite
Chemical Name
disodium diazen-1-ium-1,2,2-triolate
Molecular Formula
Na2(ONNO2)
Molecular Weight
122
Solubility
H20: 50 mg/ml,PBS (pH 7.2): 50 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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