Reactive Nitrogen Species

8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents.

JS-K is a nitric oxide (NO) donor that reacts with glutathione to generate NO at physiological pH.

A classical nitroxyl (NO-) donor

A NO donor

Tetrahydrocoptisine ((RS)-Stylopine) (Tetrahydrocoptisine) is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities.

(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS.

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities.

10-Nitrooleate (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles.

DCFH2-DA (2',7'-Dichlorofluorescein diacetate) is a cell-membrane-permeable universal oxidative stress indicator. This reagent can be used to detect reactive oxygen species (ROS), nitric oxide (NO), and to assess the overall oxidative stress level.

Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate, cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules.

Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide.

Coumarin boronic acid pinacolate ester (CBE) is a more soluble form of coumarin boronic acid that can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide.

DEPMPO is a nitrone that is used to spin trap reactive O-, N-, S-, and C-centered radicals and allow their characterization when used in association with electron spin resonance.

Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of α-lipoic acid.

DPTA NONOate is a NO donor.

Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions.

FeTPPS is a metalloporphyrin-based ONOO⁻ decomposition catalyst.

Hydroxyphenyl fluorescein (HPF) is the reagent that can directly detect highly reactive oxygen species (hROS).

MHY908 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ that increases transcriptional activity of PPARα and PPARγ in a luciferase reporter assay in AC2F rat liver cells when used at a concentration of 5 μM.

MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.

Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst.

Nitrosobenzene is a spin trap that has been used in the study of oxidative DNA damage and nitroso-compound-induced respiratory burst in neutrophils.

NO-indomethacin is a hybrid molecule of indomethacin and a nitric oxide (NO) donor.

p-Cymene is a monoterpene that is found in a variety of plants, including C.