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Aldoview

رقم الكتالوجGC79839 Copy One-Click Copy Product Info

AldoView (Compound 3) is an intermediate.

Products are for research use only. Not for human use. We do not sell to patients.

Aldoview التركيب الكيميائي

Cas No.: 1356479-94-1

الحجم السعر المخزون الكميّة
10mg
720٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


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بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of Aldoview

AldoView (Compound 3) is an intermediate. AldoView can be labeled with fluorine-18 to synthesize [ 18 F]AldoView. [ 18 F]AldoView is a highly selective aldosterone synthase PET imaging agent. AldoView can be used in imaging studies of primary aldosteronism [1].

References:
[1]. Sander K, et al. Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism. J Med Chem. 2021 Jul 8;64(13):9321-9329.

Chemical Properties of Aldoview

Cas No. 1356479-94-1 SDF
Formula C15H10F3N3 M.Wt 289.26
الذوبان DMSO: 12.5 mg/mL (43.21 mM; Need ultrasonic) Storage Store at room temperature
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Aldoview

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.4571 mL 17.2855 mL 34.571 mL
5 mM 691.4 μL 3.4571 mL 6.9142 mL
10 mM 345.7 μL 1.7285 mL 3.4571 mL
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In vivo Formulation Calculator (Clear solution) of Aldoview

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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