P450
منتجات لـ نبسب؛ P450
- القط. رقم اسم المنتج بيانات
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GC66197
α-?Terpinyl acetate
α؛ -Terpinyl acetate هو إستر أحادي التربين معزول من زيت Laurus nobilis L. الأساسي. α ؛ - أسيتات التربينيل عبارة عن ركيزة P450 2B6 تنافسية والتي ترتبط بالموقع النشط لـ P450 2B6 بقيمة Kd 5.4μ ؛ M.
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GC45208
α-hydroxy Metoprolol
α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol.
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GC63272
β-Apo-8’-carotenal
β؛ -Apo-&8#39؛-carotenal (Apocarotenal) ، وهو بروفيتامين أ كاروتينويد ، هو محفز لـ CYPlA1 و CYPlA2 في الفئران. β؛ -Apo-&8#39؛-carotenal موجود في العديد من الفواكه والخضروات.
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GC45239
δ4-Abiraterone
CB 7627, D4A
δ ، 4-أبيراتيرون هو مستقلب رئيسي للأبيراتيرون. δ ؛ 4-Abiraterone هو مثبط لـ CYP17A1 ، 3b-hydroxysteroid dehydrogenase (3β ؛ HSD) و Steroid-5a-reductase (SRD5A) وأيضًا مضاد لمستقبلات الأندروجين. -
GC40112
(±)-Climbazole-d4
(±)-Climbazole-d4 is intended for use as an internal standard for the quantification of climbazole by GC- or LC-MS.
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GC46284
(±)-Cotinine-d3
An internal standard for the quantification of cotinine
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GC40954
(±)-N-3-Benzylnirvanol
(S)-N-3-benzyl Nirvanol
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol. -
GC45269
(±)10(11)-DiHDPA
(±)10,11-DiHDPE
(±)10(11)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid. -
GC45270
(±)10(11)-EDP Ethanolamide
10,11-EDP-EA, 10,11-EDP epoxide, 10,11-epoxy Docosapentaenoic Ethanolamide
(±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). -
GC41212
(±)10(11)-EpDPA
(±)10,11-EDP, (±)10,11-EpDPE, (±)10,11-epoxy DPA, (±)10,11-epoxy Docosapentaenoic Acid
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. -
GC91064
(±)10,11-EDT
متابوليت حمض أدرينيك
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GC40279
(±)11(12)-DiHET
(±)11,12DiHETrE
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. -
GC49439
(±)11(12)-DiHET MaxSpec® Standard
(±)11,12-DiHETrE
A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications -
GC40466
(±)11(12)-EET
(±)11,12-EpETrE
(± ؛) 11 (12) -EET هو مثبط للالتهاب NLRP3. -
GC45271
(±)11(12)-EET Ethanolamide
(±)11,12-EpETrE Ethanolamide
Arachidonoyl ethanolamide (AEA; anandamide) is an endogenous lipid neurotransmitter with cannibingeric activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. -
GC40841
(±)11(12)-EET methyl ester
(±)11,12EpETrE methyl ester
(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC45922
(±)11(12)-EET-d11 methyl ester
(±)11,12-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC40386
(±)11(12)-EpETE
(±)11,12-EEQ, (±)11,12-Epoxyeicosatetraenoic Acid
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms. -
GC41143
(±)11,12-DiHETE
(±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase.
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GC40802
(±)12(13)-DiHOME
Isoleukotoxin diol
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
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GC46256
(±)12(13)-DiHOME-d4
Isoleukotoxin diold4
A neuropeptide with diverse biological activities -
GC40539
(±)12(13)-EpOME
(±)12,13-EODE, Isoleukotoxin, (±)-Vernolic Acid
(±)12(13)-EpOME is the 12,13-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. -
GC46257
(±)12(13)-EpOME-d4
(±)12,13-EODE-d4, Isoleukotoxin-d4, (±)Vernolic Acidd4
A neuropeptide with diverse biological activities -
GC48738
(±)12-HETE-d8
(±)12-Hydroxyeicosatetraenoic Acid-d8
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GC41648
(±)13(14)-DiHDPA
13(14)-DiHDPA, 13(14)-DiHDoPE, 13,14-DiHDPE
(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. -
GC41191
(±)13(14)-EpDPA
(±)13,14-EDP, (±)13,14-EpDPE, (±)13,14-epoxy DPA, (±)13,14-epoxy Docosapentaenoic Acid
(± ؛) 13 (14) -EpDPA (13،14-EpDPE) هو نتاج تفاعل السيتوكروم P-450 إيبوكسيجيناز مع حمض الدوكوساهيكسانويك (DHA). -
GC91066
(±)13,14-DiHDoTrE
أوكسيليبين
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GC91065
(±)13,14-EDT
متابوليت حمض أدرينيك
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GC40268
(±)14(15)-DiHET
(±)14,15DiHETrE
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. -
GC41116
(±)14(15)-DiHETE
(±)14,15dihydroxyeicosa5,8,11,17Tetraenoic Acid
Eicosapentaenoic acid is an ω-3 fatty acid abundantly available in marine organisms. -
GC40430
(±)14(15)-EET
(±)14,15-EET, (±)14,15-EpETrE
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.
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GC41650
(±)14(15)-EET Ethanolamide
(±)14,15EpETrE Ethanolamide, (±)14(15)Epoxy Eicosatrienoyl Ethanolamide
Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. -
GC40835
(±)14(15)-EET methyl ester
(±)14,15EpETrE methyl ester
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC45920
(±)14(15)-EET-d11 methyl ester
(±)14,15-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC41651
(±)14(15)-EET-SI
14,15-EpETrE-SI, 14(15)-EET-SI, 14(15)EETsulfonimide
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. -
GC41652
(±)14(15)-EpEDE
(±)14,15Epoxyeicosadienoic Acid
8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid, is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases. -
GC40888
(±)14(15)-EpEDE methyl ester
(±)14,15Epoxyeicosadienoic Acid methyl ester
(±)14(15)-EpEDE is an EpEDE formed from 8,11,14-eicosatrienoic acid, also known as dihomo-γ-linolenic acid. -
GC40360
(±)14(15)-EpETE
(±)14,15 EEQ, (±)14,15epoxy Eicosatetraenoic Acid
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. -
GC41653
(±)16(17)-DiHDPA
(±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid.
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GC41194
(±)16(17)-EpDPA
(±)16,17 EDP, (±)16,17-epoxy Docosapentaenoic Acid, (±)16,17-epoxy DPA, (±)16,17-EpDPE
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.
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GC41195
(±)16(17)-EpDPA MaxSpec® Standard
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.
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GC91067
(±)16,17-EDT
متابوليت حمض أدرينيك
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GC40434
(±)16-HETE
(±)16-Hydroxyeicosatetraenoic Acid
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. -
GC41117
(±)17(18)-DiHETE
(±)17,18-dihydroxy-eicosa-5,8,11,14-Tetraenoic Acid
Eicosapentaenoic acid is an ω-3 fatty acid abundantly available in marine organisms. -
GC46260
(±)17(18)-EpETE
(±)17,18-EEQ, (±)17,18-epoxy Eicosatetraenoic Acid
A neuropeptide with diverse biological activities -
GC41318
(±)17(18)-EpETE methyl ester
(±)17,18-EEQ methyl ester, (±)17,18-epoxy Eicosatetraenoic Acid methyl ester
(±)17(18)-EpETE methyl ester is an analog of the eicosapentaenoic acid (EPA) metabolite (±)17(18)-EpETE that is more lipid soluble. -
GC41288
(±)17(18)-EpETE-Ethanolamide
17,18-EEQ-EA, (±)17,18-EEQ-Ethanolamide, (±)17(18)-EpETE-EA, 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. -
GC40435
(±)17-HETE
(±)-Hydroxyeicosatetraenoic Acid
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. -
GC40436
(±)18-HETE
(±)18-Hydroxyeicosatetraenoic Acid
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. -
GC41654
(±)19(20)-DiHDPA
(±)19,20DiHDoPE
Docosahexaenoic acid is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. -
GC40388
(±)19(20)-DiHDTE
(±)19(20)-DiHDoTE
(±)19(20)-DiHDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid. -
GC41655
(±)19(20)-EDP Ethanolamide
19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). -
GC41199
(±)19(20)-EpDPA
(±)19,20 EDP, (±)19,20-epoxy Docosapentaenoic Acid, (±)19,20-epoxy DPA, (±)19,20-EpDPE
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. -
GC40905
(±)19(20)-EpDTE
(±)19(20)-EpDoTE
(±)19(20)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid. -
GC41656
(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol
(±)214,15EG
2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. -
GC41201
(±)4(5)-DiHDPA lactone
(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET, which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5 double bond.
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GC41660
(±)4(5)-EpDPA methyl ester
(±)4,5EDP methyl ester, (±)4,5epoxy Docosapentaenoic Acid methyl ester, (±)4,5epoxy DPA methyl ester, (±)4(5)-EpDPE methyl ester
(±)4(5)-EpDPA methyl ester is a derivative of (±)4(5)-EpDPA which is stable enough to ship and handle routinely. -
GC40437
(±)5(6)-DiHET lactone
(±)5,6DiHETrE lactone
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. -
GC40271
(±)5(6)-DiHET MaxSpec® Standard
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
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GC41119
(±)5(6)-DiHETE
Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.
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GC40363
(±)5(6)-DiHETE lactone
Eicosapentaenoic acid is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases.
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GC40438
(±)5(6)-EET
(±)5,6EpETrE
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. -
GC41662
(±)5(6)-EET Ethanolamide
(±)5,6EpETrE Ethanolamide
Arachidonyl ethanolamide is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. -
GC40836
(±)5(6)-EET methyl ester
(±)5,6EpETrE methyl ester
(±)5(6)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC46262
(±)5(6)-EET-d11
(±)5,6-EET-d11
A neuropeptide with diverse biological activities -
GC45919
(±)5(6)-EET-d11 methyl ester
(±)5,6-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC41319
(±)5(6)-EpETE methyl ester
(±)5,6EEQ methyl ester, (±)5,6epoxy Eicosatetraenoic Acid methyl ester
(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely. -
GC41663
(±)7(8)-DiHDPA
(±)7(8)-DiHDPA is a major metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.
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GC40389
(±)7(8)-DiHDTE
(±)7(8)-DiHDoTE
(±)7(8)-DiHDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid. -
GC41203
(±)7(8)-EpDPA
(±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy DPA, (±)7,8-epoxy Docosapentaenoic Acid
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. -
GC40906
(±)7(8)-EpDTE
(±)7(8)-EpDoTE
(±)7(8)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid. -
GC91062
(±)7(S),8(R)-EDT
أوكسيليبين
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GC40272
(±)8(9)-DiHET
(±)8,9DiHETrE
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. -
GC40440
(±)8(9)-EET
(±)8,9EpETrE
(±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid. -
GC41665
(±)8(9)-EET Ethanolamide
(±)8,9-EET Ethanolamide
Arachidonoyl ethanolamide (AEA; anandamide) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. -
GC40838
(±)8(9)-EET methyl ester
(±)8,9EpETrE methyl ester
(±)8(9)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. -
GC46264
(±)8(9)-EET-d11
(±)8,9-EET-d11, (±)8,9-EpETrE-d11
A neuropeptide with diverse biological activities -
GC45921
(±)8(9)-EET-d11 methyl ester
(±)8,9-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC40365
(±)8(9)-EpETE
(±)8,9-EEQ, (±)8,9-epoxy Eicosatetraenoic Acid
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. -
GC41120
(±)8,9-DiHETE
(±)8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid.
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GC40801
(±)9(10)-DiHOME
Leukotoxin diol
(± ؛) 9 (10) -DiHOME هو رفاق سباق 9،10-DiHOME. -
GC40540
(±)9(10)-EpOME
Coronaric Acid, (±)9,10EODE, Leukotoxin
(±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. -
GC40443
(±)9-HETE
(±)9-Hydroxyeicosatetraenoic Acid
(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. -
GC46268
(±)9-HETE-d8
(±)9-Hydroxyeicosatetraenoic Acid-d8
A neuropeptide with diverse biological activities -
GC41346
(+)-Cedrol
(+)-Cedrol is a sesquiterpene alcohol that has been used in Cannabis testing and has diverse biological activities.
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GC12404
(+)-Ketoconazole
R 41400
(+) - كيتوكونازول ((+) - R 41400) هو عامل مضاد للفطريات إيميدازول ، وهو مثبط لـ CYP3A4 -
GC30424
(-)-Cephaeline dihydrochloride (NSC 32944)
(-) - Cephaeline dihydrochloride (NSC 32944) هو مثبط انتقائي لـ CYP2D6 مع IC50 لـ 121 μ ؛ M.
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GC18622
(2'S)-Nicotine-1-oxide
Nicotine-N-oxide
(2'S)-Nicotine-1-oxide is a metabolite of nicotine . -
GC41694
(3S)-hydroxy Quinidine
(3S)-hydroxy Quinidine is an active quinidine metabolite.
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GC39746
(3S,5S)-Atorvastatin
(3S ، 5S) - أتورفاستاتين هو متماثل غير نشط من أتورفاستاتين
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GC91418
(E)-KPT-330
KTP-330; trans Selinexor
(E)-KPT-330 هو متابوليت لمثبط exportin 1 (XPO1/CRM1) selinexor.
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GC49189
(E/Z)-4-hydroxy Tamoxifen-d5
Afimoxifene-d5, 4-OHT-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen -
GC18286
(R)-Mephenytoin
(-)-Mephenytoin
(R) -Mephenytoin ((-) - Mephenytoin) ، R-enantiomer لميفينيتوين -
GC41720
(R)-Omeprazole (sodium salt)
(R)-OMEP, (R)-OMP, (R)-OMZ
(R)-Omeprazole is the inactive isomer of omeprazole, a gastric proton-pump inhibitor. -
GC14486
(S)-Mephenytoin
(S)-5-Ethyl-3-methyl-5-phenylhydantoin
(S) - ميفينيتوين ((+) - ميفينيتوين) هو عامل مضاد للاختلاج -
GC20027
(±)5(6)-DiHET MaxSpec® Standard
(±)5,6-DiHETrE
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
-
GC90942
1,2,3,4,6,7,8,9-Octachlorodibenzofuran
مركب الديوكسين المشابه للبولي كلوريد داي بنزوفوران
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GC90937
1,2,3,4,7,8,9-Heptachlorodibenzofuran
مركب الديوكسين المشابه للبولي كلوريد داي بنزوفوران
-
GC90938
1,2,3,4,7,8-Hexachlorodibenzofuran
مركب الديوكسين المشابه للبولي كلوريد داي بنزوفوران
-
GC41837
1,3,7-Trimethyluric Acid
8-oxo Caffeine, NSC 11259
1،3،7-حمض تريميثيلوريك هو مستقلب الكافيين. يمكن تقييم نسبة التمثيل الغذائي 1.3،7-Trimethyluric Acid إلى الكافيين كمؤشر حيوي لوصف التباين في نشاط CYP3A في مجموعة.