Benralizumab (Synonyms: MEDI-563; BIW-8405) |
| رقم الكتالوجGC39346 |
Benralizumab (MEDI-563) هو أحد مستقبلات الإنترلوكين -5 α (IL-5Rα) الموجه وحيدة النسيلة والذي يؤدي إلى استنفاد مباشر وسريع وشبه كامل للحمضات عن طريق السمية الخلوية المعززة التي تعتمد على الجسم المضاد
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Cas No.: 1044511-01-4
Sample solution is provided at 25 µL, 10mM.
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Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma[1].
[1]. Menzies-Gow A, et al. Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial. ERJ Open Res. 2019 Sep 25;5(3). pii: 00009-2019.
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