BMS-986482 is a CRBN -mediated IKZF1-4 ( Ikaros family zinc finger 1-4 ) molecular glue degrader. BMS-986482's activity is driven by a non-traditional CELMoD core that selectively degrades the IKZF protein family. BMS-986482 can be used for the research of advanced solid tumors [1].
In Vivo, BMS-986482 induces robust tumor growth inhibition in syngeneic mouse models[1].
References:
[1]. ACS Spring 2026: First Time Disclosures
In Vivo, BMS-986482 induces robust tumor growth inhibition in syngeneic mouse models[1].
References:
[1]. ACS Spring 2026: First Time Disclosures