Cyproconazole (Synonyms: SAN 619F) |
| رقم الكتالوجGC30173 |
سيبروكونازول هو مبيد فطري تريازول يستخدم في الزراعة لحماية المحاصيل من مجموعة واسعة من مسببات الأمراض الفطرية.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 94361-06-5
Sample solution is provided at 25 µL, 10mM.
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Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens.In vitro: Cyproconazole has been shown to cause a dose dependent inhibition of progesterone production in human placental cells in vitro. cyproconazole exhibited the lowest capacity to increase CYP1A1 and were not able to activate the AhR in the transactivation assay. [1]In vivo: Cyproconazole, a triazole fungicide, causes hepatocellular adenomas and carcinomas in CD-1 mice at dose levels of 100 and 200 ppm. In wild-type mice, 200 ppm cyproconazole caused liver hypertrophy, increased liver weight and cell proliferation, single-cell necrosis and fat vacuolation. [2]
[1]. Rieke S et al. Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a humanplacental cell line. Int J Environ Res Public Health. 2014 Sep 17;11(9):9660-79. [2]. Peffer RC et al. Mouse liver effects of cyproconazole, a triazole fungicide: role of the constitutive androstane receptor. Toxicol Sci. 2007 Sep;99(1):315-25.
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