الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>IMP

IMP

رقم الكتالوجGC19718

IMP هو مستقلب داخلي.

Products are for research use only. Not for human use. We do not sell to patients.

IMP التركيب الكيميائي

Cas No.: 131-99-7

الحجم السعر المخزون الكميّة
25mg
45٫00
متوفر
50mg
72٫00
متوفر
100mg
117٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

    GlpBio Citations
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Sample solution is provided at 25 µL, 10mM.

Description of IMP

Inosinic acid (IMP) is a purine ribonucleoside 5'-monophosphate having hypoxanthine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purine ribonucleoside 5'-monophosphate and an inosine phosphate. It is a conjugate acid of an IMP(2-).

IMP is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).

Chemical Properties of IMP

Cas No. 131-99-7 SDF
Canonical SMILES O[C@]([C@](O)([H])[C@]1([H])N2C=NC3=C2N=CN=C3O)([H])[C@@](O1)([H])COP(O)(O)=O
Formula C10H13N4O8P M.Wt 348.21
الذوبان insoluble in EtOH; >70 mg/mL in Water Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of IMP

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8718 mL 14.3592 mL 28.7183 mL
5 mM 0.5744 mL 2.8718 mL 5.7437 mL
10 mM 0.2872 mL 1.4359 mL 2.8718 mL
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In vivo Formulation Calculator (Clear solution) of IMP

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for IMP

Average Rating: 5 ★★★★★ (Based on Reviews and 18 reference(s) in Google Scholar.)

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