الصفحة الرئيسية>>Signaling Pathways>> Angiogenesis>>LYG-202

LYG-202

رقم الكتالوجGC40865

LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities.

Products are for research use only. Not for human use. We do not sell to patients.

LYG-202 التركيب الكيميائي

Cas No.: 1175077-25-4

الحجم السعر المخزون الكميّة
1mg
42٫00
متوفر
5mg
156٫00
متوفر
10mg
292٫00
متوفر
25mg
675٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

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  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities. It inhibits proliferation of HepG2, MCF-7, HeLa, BGC-823, MDA-MB-435, and HCT116 cancer cells in vitro (IC50s = 4.74-27.70 μM) via induction of apoptosis and dissipation of the mitochondrial membrane potential. LYG-202 reduces tumor growth in S180 sarcoma cell-inoculated mice. It also inhibits VEGF-stimulated human umbilical vein endothelial cells (HUVEC) cell migration and tube formation in vitro and decreases capillary sprouting in isolated rat aortic rings and the chicken chorioallantoic membrane (CAM) model of angiogenesis.

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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