Apoptosis Inducers
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Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.
Products Related to Apoptosis Inducers(42)
- GC150842-Methoxyestradiol (2-MeOE2)CAS: 362-07-2Purity: >98.00%
2-Methoxyestradiol (2-MeOE2/2-Me) is an HIF-1α inhibitor.
- GC15878Atractyloside Dipotassium SaltCAS: 102130-43-8Purity: >99.50%
Inhibitor of ADP/ATP translocases
- GC16116CostunolideCAS: 553-21-9Purity: >98.00%
Costunolide is a multi-target NF-κB inhibitor with diverse biological activities.
- GC16375(±)-Jasmonic Acid methyl esterCAS: 39924-52-2Purity: >98.00%
(± ؛) - حمض جاسمونيك ميثيل استر هو مستقلب داخلي.
- GC16866Actinomycin DCAS: 50-76-0Purity: >98.00%
مانع تفاعل الحمض النووي مع المتكلمات الجينية ذو التأثير المضاد للسرطان
- GC18044TrabectedinCAS: 114899-77-3Purity: >99.50%
Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin can selectively inhibit transcription factors associated with DNA damage repair and block the DNA nucleotide excision repair pathway, leading to DNA double-strand breaks and tumor cell apoptosis. Trabectedin can also regulate the tumor microenvironment and indirectly exert antitumor effects by inhibiting the activity of tumor-associated macrophages. Trabectedin is often used in the study of soft tissue sarcoma and ovarian cancer.
- GC19203Lipopolysaccharides from Escherichia coli O111:B4
يتم تنقية اللبوساكاريدات الدهنية (LPSs) بواسطة كروماتوغرافيا التصفية عبر الجيل.
- GC14312MeisoindigoCAS: 97207-47-1Purity: >98.00%
Meisoindigo (Dian III) ، أحد مشتقات Indirubin ، يوقف دورة الخلية في مرحلة G0 / G1 ويحفز موت الخلايا المبرمج في خلايا سرطان الدم النخاعي الحاد الأولي (AML)يظهر Meisoindigo نشاطًا عاليًا مضادًا للورم
- GC15036Raltegravir potassium saltCAS: 871038-72-1Purity: >98.00%
رالتجرافير (MK 0518) البوتاسيوم هو مثبط قوي للإنزيم (IN) ، يستخدم لعلاج عدوى فيروس نقص المناعة البشرية.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC15084 | 2-Methoxyestradiol (2-MeOE2) | 362-07-2 | >98.00% | |
2-Methoxyestradiol (2-MeOE2/2-Me) is an HIF-1α inhibitor. | ||||
| GC15484 | Deguelin | 522-17-8 | >99.00% | |
Deguelin is one of four major naturally occurring rotenoids isolated from root extracts and is best recognized as a NADH: ubiquinone oxidoreductase (complex I) inhibitor, resulting in significant alterations in mitochondrial function. | ||||
| GC15878 | Atractyloside Dipotassium Salt | 102130-43-8 | >99.50% | |
Inhibitor of ADP/ATP translocases | ||||
| GC16037 | 7BIO | 916440-85-2 | >98% | |
7BIO (7-بروموينديروبين-3-أوكسيم) هو أحد مشتقات الإندروبين | ||||
| GC16055 | SMIP004 | 143360-00-3 | >98.50% | |
| GC16116 | Costunolide | 553-21-9 | >98.00% | |
Costunolide is a multi-target NF-κB inhibitor with diverse biological activities. | ||||
| GC16375 | (±)-Jasmonic Acid methyl ester | 39924-52-2 | >98.00% | |
(± ؛) - حمض جاسمونيك ميثيل استر هو مستقلب داخلي. | ||||
| GC16661 | Citrinin | 518-75-2 | >98.00% | |
ميكوتوكسين يحفز الخلايا على التصلب البرمجي | ||||
| GC16866 | Actinomycin D | 50-76-0 | >98.00% | |
مانع تفاعل الحمض النووي مع المتكلمات الجينية ذو التأثير المضاد للسرطان | ||||
| GC17131 | Streptozocin | 18883-66-4 | >99.00% | |
عامل مسبب لمرض السكري يستهدف خلايا بيتا. | ||||
| GC17874 | Matrine | 519-02-8 | >98.00% | |
Matrine is an alkaloid found in Sophora japonica plants that acts as a kappa opioid receptor and μ-receptor agonist. | ||||
| GC17969 | CHM 1 | 154554-41-3 | >98% | |
An inhibitor of tubulin polymerization | ||||
| GC18044 | Trabectedin | 114899-77-3 | >99.50% | |
Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin can selectively inhibit transcription factors associated with DNA damage repair and block the DNA nucleotide excision repair pathway, leading to DNA double-strand breaks and tumor cell apoptosis. Trabectedin can also regulate the tumor microenvironment and indirectly exert antitumor effects by inhibiting the activity of tumor-associated macrophages. Trabectedin is often used in the study of soft tissue sarcoma and ovarian cancer. | ||||
| GC19203 | Lipopolysaccharides from Escherichia coli O111:B4 | - | - | |
يتم تنقية اللبوساكاريدات الدهنية (LPSs) بواسطة كروماتوغرافيا التصفية عبر الجيل. | ||||
| GN10421 | Kaempferol | 520-18-3 | >98.50% | |
مركب فلافونويد غذائي | ||||
| GC14312 | Meisoindigo | 97207-47-1 | >98.00% | |
Meisoindigo (Dian III) ، أحد مشتقات Indirubin ، يوقف دورة الخلية في مرحلة G0 / G1 ويحفز موت الخلايا المبرمج في خلايا سرطان الدم النخاعي الحاد الأولي (AML)يظهر Meisoindigo نشاطًا عاليًا مضادًا للورم | ||||
| GC15035 | PM00104 | 308359-57-1 | >98% | |
Potent antimyeloma agent | ||||
| GC15036 | Raltegravir potassium salt | 871038-72-1 | >98.00% | |
رالتجرافير (MK 0518) البوتاسيوم هو مثبط قوي للإنزيم (IN) ، يستخدم لعلاج عدوى فيروس نقص المناعة البشرية. | ||||