Pain Research

D-Amino acid oxidase inhibitor is an inhibitor of D-amino acid oxidase (DAAO) with IC50 values of 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively.

DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities.

Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons.

An esterified form of diclofenac

Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac.

DPDPE is a synthetic enkephalin peptide and δ-opioid receptor agonist (Ki = 2.7 nM in rat brain homogenates).

Endomorphin 1 is an endogenous neuropeptide and μ-opioid receptor agonist (Ki = 0.36 nM) that has analgesic, positive reinforcing, and gastrointestinal properties.

Endomorphin 2 (trifluoroacetate salt) is a high-affinity and highly selective agonist of the μ-opioid receptor (K i = 0.69nM).

Galanin is a neuropeptide with diverse biological activities.

GAT211 هو مُعدِّل خيفي إيجابي لمستقبلات القنب 1 (CB1R)

N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities.

The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2).

Iperoxo (يوديد) هو عامل خارق قوي لمستقبلات الأسيتيل كولين المسكارينية (mAChR).

Met-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ- and μ-opioid receptors (Kis = 0.65 and 1.7 nM, respectively).

Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 μM) with selectivity over L-type Ca2+ channels and GABAA receptors.

Several different arachidonoyl amino acids, including N-arachidonoyl-L-alanine (NALA), have been isolated and characterized from bovine brain.

Neurotensin (8-13) is a neuropeptide that corresponds to the C-terminal residues 8-13 of neurotensin that binds to rat synaptic membranes with a Ki value of 13 nM.

Neurotensin (trifluoroacetate salt) is a neuropeptide composed of 13 amino acids, which functions as a neurotransmitter, hormone, and neuromodulator.

N-Oleoyl proline is an N-acyl amine that has been detected in bovine brain extracts and D.

N-Palmitoyl Glycine (N-palmitoyl glycine) ، دهون داخلية تعمل كمعدل لتدفق الكالسيوم وإنتاج أكسيد النيتريك (NO) في الخلايا العصبية الحسية.

Oleoyl-D-lysine is an inhibitor of glycine transporter 2a (GlyT2a).

حمض بامويك هو ناهض GPR35 قوي مع EC50 من 79 نانومتر

Prochlorperazine is a dopamine D2 receptor antagonist with Ki values of 4.7 and 2.9 nM for rat recombinant D2 receptors in CHO cells and rat striatal membranes, respectively.

Reduced haloperidol is an active metabolite of haloperidol.