Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC72791Delmitide acetateCAS: 501019-16-5Purity: >98.00%
Delmitide acetate هو فموي نشط -ايزومر decapeptide مع نشاط قوي ضد الالتهاب.
- GC72858Avenanthramide ACAS: 108605-70-5Purity: >99.00%
Avenanthramide A هو ptoalexin، الذي يمكن العثور عليه في الشوفان (Avena sativa L.).
- GC72995MnTE-2-PyP chlorideCAS: 219818-60-7Purity: >95.00%
MnTE-2-PyP chloride هو زبال ROS وحامي إشعاعي قوي.
- GC73031Salpyran dihydrochloridePurity: >99.00%
Salpyran dihydrochloride هو مخلب انتقائي Cu(II) مع إمكانية علاجية.
- GC73225ROS-generating agent 1CAS: 2369030-41-9Purity: >99.00%
يقوم ROS-generating agent 1 (المركب 2c) بتعديل تساهمي لبقايا Sec-498 من TrxR لتوليد ROS.
- GC74090Dimethyl fumarate-d2CAS: 23057-98-9Purity: >99.00%
Dimethyl fumarate-d2 هو الديوتيريوم المسمى ديمتل فومارات.
- GC74270PenduletinCAS: 569-80-2Purity: >99.00%
Penduletin هو فلافون، الذي يمكن عزله من Brickelia pendula و Vitex negundo.
- GC746683-Methoxy-9H-CarbazoleCAS: 18992-85-3Purity: >99.00%
يحفز 3-Methoxy-9H-Carbazole أنشطة كاسباس 3 والتوليد الخلوي لأنواع الأكسجين التفاعلي.
- GC81540Brevicidine TFAPurity: >97.50%
Brevicidine TFA is an antimicrobial peptide with selective bactericidal activity against Gram-negative pathogens.
- GC81541BMAP-27 acetatePurity: >98.00%
BMAP-27 acetate is a cationic amphipathic α-helical antimicrobial peptide with anticancer activity.
- GC815427-O-Galloyl-D-sedoheptuloseCAS: 233690-85-2Purity: >98%
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound.
- GC81543GPX4-IN-19CAS: 3102894-57-2Purity: >99.00%
GPX4-IN-19 is an effective GPX4 inhibitor ( IC 50 = 0.311 μM), covalently binds to the Sec 46 site of GPX4.
- GC81544Copper ionophore ICAS: 101264-90-8Purity: >98.00%
Copper ionophore I is an efficient copper ion carrier.
- GC81545Ferroptosis inducer-12Purity: >96.00%
Ferroptosis inducer-12 is a potent and selective ferroptosis inducer.
- GC81547Geranyl isovalerateCAS: 109-20-6Purity: >96.50%
Geranyl isovalerate is a chemical component that can be extracted from Argyreia Nervosa.
- GC81548CIGB-552 TFAPurity: >98.00%
CIGB-552 TFA is a cell-penetrating peptide with anti-tumor properties with the IC 50 of 23 μM in H460 cells.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC72755 | Tempol-d17,15N | 90429-66-6 | - | |
Tempol-d17,15N هو الديوتيريوم المسمى تيمبول. | ||||
| GC72791 | Delmitide acetate | 501019-16-5 | >98.00% | |
Delmitide acetate هو فموي نشط -ايزومر decapeptide مع نشاط قوي ضد الالتهاب. | ||||
| GC72858 | Avenanthramide A | 108605-70-5 | >99.00% | |
Avenanthramide A هو ptoalexin، الذي يمكن العثور عليه في الشوفان (Avena sativa L.). | ||||
| GC72888 | CPS-11 | 145945-21-7 | >99.00% | |
CPS-11 (N-(droxymetl)thalidomide) نظير الثاليدوميد، هو عامل قوي ضد السرطان. | ||||
| GC72995 | MnTE-2-PyP chloride | 219818-60-7 | >95.00% | |
MnTE-2-PyP chloride هو زبال ROS وحامي إشعاعي قوي. | ||||
| GC73031 | Salpyran dihydrochloride | - | >99.00% | |
Salpyran dihydrochloride هو مخلب انتقائي Cu(II) مع إمكانية علاجية. | ||||
| GC73188 | SFI003 | 2361332-90-1 | >99.00% | |
SFI003 هو مثبط SRSF3 الذي يحفز موت الخلايا المبرمج عن طريق محور SRSF3/DHCR24/ROS ويظهر تأثيرات قوية مضادة للورم في المختبر وفي الجسم الحي. | ||||
| GC73212 | TH-6 | 3031349-25-1 | >95.00% | |
TH-6 هو مثبط قوي HDAC مع IC50s 0.115، 0.135، 0.242، 0.138، 2.120 µM ل HDAC1، HDAC2، HDAC3، HDAC6، HDAC8، على التوالي. | ||||
| GC73225 | ROS-generating agent 1 | 2369030-41-9 | >99.00% | |
يقوم ROS-generating agent 1 (المركب 2c) بتعديل تساهمي لبقايا Sec-498 من TrxR لتوليد ROS. | ||||
| GC73543 | FC-116 | 2417298-29-2 | >98.00% | |
FC-116 هو مثبط توبيلين الذي يمنع بشكل فعال نمو الورم في الفئران. | ||||
| GC74090 | Dimethyl fumarate-d2 | 23057-98-9 | >99.00% | |
Dimethyl fumarate-d2 هو الديوتيريوم المسمى ديمتل فومارات. | ||||
| GC74256 | Condurango glycoside A | 11051-90-4 | >95.00% | |
Condurango glycoside A هو منشط p53. | ||||
| GC74270 | Penduletin | 569-80-2 | >99.00% | |
Penduletin هو فلافون، الذي يمكن عزله من Brickelia pendula و Vitex negundo. | ||||
| GC74668 | 3-Methoxy-9H-Carbazole | 18992-85-3 | >99.00% | |
يحفز 3-Methoxy-9H-Carbazole أنشطة كاسباس 3 والتوليد الخلوي لأنواع الأكسجين التفاعلي. | ||||
| GC81540 | Brevicidine TFA | - | >97.50% | |
Brevicidine TFA is an antimicrobial peptide with selective bactericidal activity against Gram-negative pathogens. | ||||
| GC81541 | BMAP-27 acetate | - | >98.00% | |
BMAP-27 acetate is a cationic amphipathic α-helical antimicrobial peptide with anticancer activity. | ||||
| GC81542 | 7-O-Galloyl-D-sedoheptulose | 233690-85-2 | >98% | |
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound. | ||||
| GC81543 | GPX4-IN-19 | 3102894-57-2 | >99.00% | |
GPX4-IN-19 is an effective GPX4 inhibitor ( IC 50 = 0.311 μM), covalently binds to the Sec 46 site of GPX4. | ||||
| GC81544 | Copper ionophore I | 101264-90-8 | >98.00% | |
Copper ionophore I is an efficient copper ion carrier. | ||||
| GC81545 | Ferroptosis inducer-12 | - | >96.00% | |
Ferroptosis inducer-12 is a potent and selective ferroptosis inducer. | ||||
| GC81546 | iMQT_020 | 2463893-46-9 | >99.00% | |
iMQT_020 is a selective allosteric SLC1A5_var inhibitor. | ||||
| GC81547 | Geranyl isovalerate | 109-20-6 | >96.50% | |
Geranyl isovalerate is a chemical component that can be extracted from Argyreia Nervosa. | ||||
| GC81548 | CIGB-552 TFA | - | >98.00% | |
CIGB-552 TFA is a cell-penetrating peptide with anti-tumor properties with the IC 50 of 23 μM in H460 cells. | ||||
| GC81553 | YRDC-IN-1 | 3120494-74-5 | >93.50% | |
YRDC-IN-1 is a blood-brain barrier-permeable YRDC inhibitor. | ||||