mTOR
MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.
Products Related to mTOR(132)
- GC72768Desmethyl-VS-5584 hydrochloridePurity: >98.00%
Desmethyl-VS-5584 hydrochloride هو نظير ثنائي الميثيل من VS-5584، وهو مثبط ثنائي فعال وانتقائي mTOR/PI3K، مع بنية بيريميدين [2,3-d].
- GC72931HTH-01-091 TFAPurity: >98.00%
مثبط HTH-01-091 TFA هو مثبط فعال وانتقائي لسحابة الليوسين كيناز الأمومي (MELK)، مع IC50 من 10.5 نانومتر.
- GC74029ASCT2-IN-1CAS: 3032651-18-3Purity: >98.00%
ASCT2-IN-1 (مركب 20k) هو مثبط ASCT2 مع قيم IC50 من 5.6 ميكرومتر و 3.5 ميكرومتر في الخلايا A549 و HEK293، على التوالي.
- GC79141T7 Peptide TFAPurity: >98.00%
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor.
- GC79231RMC-4998 TFAPurity: >99.00%
RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant.
- GC79326Tirzepatide sodiumPurity: >98.00%
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist.
- GC79339Anti-CD160 Antibody (MAT 302)Purity: >97.00%
Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160.
- GC79430Anti-IL11 Antibody (X203, Mouse IgG)Purity: >99.00%
Anti-IL11 Antibody (X203, Mouse IgG ) is an antibody targeting IL-11.
- GC79816CryptolepineCAS: 480-26-2Purity: >98%
Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties.
- GC80852Gedatolisib-d 8Purity: >98.50%
Gedatolisib -d 8 (PKI-587-d 8 ) is the deuterium labeled Gedatolisib.
- GC81042PI3K/mTOR ligand-1CAS: 1197160-66-9Purity: >97.00%
PI3K/mTOR ligand-1 is a ligand for the target protein of PROTAC ( PI3K / mTOR ).
- GC81682Sialorphin TFAPurity: >97.00%
Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC72768 | Desmethyl-VS-5584 hydrochloride | - | >98.00% | |
Desmethyl-VS-5584 hydrochloride هو نظير ثنائي الميثيل من VS-5584، وهو مثبط ثنائي فعال وانتقائي mTOR/PI3K، مع بنية بيريميدين [2,3-d]. | ||||
| GC72931 | HTH-01-091 TFA | - | >98.00% | |
مثبط HTH-01-091 TFA هو مثبط فعال وانتقائي لسحابة الليوسين كيناز الأمومي (MELK)، مع IC50 من 10.5 نانومتر. | ||||
| GC72950 | NEO214 | 1361198-80-2 | >98.00% | |
NEO214 هو مثبط الالتهام الذاتي ومترافق تساهمي من مثبط PDE4 رولبرام وكحول بيريليل. | ||||
| GC73642 | ALK-IN-26 | 2447607-85-2 | >99.00% | |
ALK-IN-26 هو مثبط ALK مع قيمة IC50 من 7.0 ميكرومتر ALK تيروزين كيناز. | ||||
| GC73678 | RMC-4998 | 2642037-07-6 | >96.00% | |
RMC-4998 هو مثبط نشط عن طريق الفم يستهدف الحالة النشطة أو المرتبطة GTP من الطافرة KRASG12C. | ||||
| GC73729 | IBL-302 | 1414455-21-2 | >98.00% | |
IBL-302 (AMU302) هو مثبط ثنائي الإشارة متاح عن طريق الفم من PIM و PI3K/AKT/mTOR مع نشاط ضد سرطان الثدي وورم الخلايا البدائية العصبية. | ||||
| GC73974 | SKI-349 | 727686-80-8 | >99.50% | |
SKI-349 هو مثبط مزدوج الهدف من sphingosine كيناز 1/2 (SPHK1/2) وتجميع الأنابيب الدقيقة (MDA). | ||||
| GC73992 | KTC1101 | 2764833-47-6 | >98.00% | |
KTC1101 هو مثبط PI3K نشط عن طريق الفم. | ||||
| GC74029 | ASCT2-IN-1 | 3032651-18-3 | >98.00% | |
ASCT2-IN-1 (مركب 20k) هو مثبط ASCT2 مع قيم IC50 من 5.6 ميكرومتر و 3.5 ميكرومتر في الخلايا A549 و HEK293، على التوالي. | ||||
| GC74030 | ASCT2-IN-2 | - | >99.00% | |
ASCT2-IN-2 (مركب 25e) هو مثبط ASCT2 مع IC50 من 5.14 ميكرومتر. | ||||
| GC74689 | WRX606 | 899937-47-4 | >95.00% | |
WRX606 هو مثبط لمركب mTOR 1 (mTORC1). | ||||
| GC78981 | HBS-101 | - | >99.50% | |
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor ( K D = 38.4 nM). | ||||
| GC79141 | T7 Peptide TFA | - | >98.00% | |
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor. | ||||
| GC79231 | RMC-4998 TFA | - | >99.00% | |
RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant. | ||||
| GC79326 | Tirzepatide sodium | - | >98.00% | |
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist. | ||||
| GC79339 | Anti-CD160 Antibody (MAT 302) | - | >97.00% | |
Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160. | ||||
| GC79430 | Anti-IL11 Antibody (X203, Mouse IgG) | - | >99.00% | |
Anti-IL11 Antibody (X203, Mouse IgG ) is an antibody targeting IL-11. | ||||
| GC79816 | Cryptolepine | 480-26-2 | >98% | |
Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties. | ||||
| GC80852 | Gedatolisib-d 8 | - | >98.50% | |
Gedatolisib -d 8 (PKI-587-d 8 ) is the deuterium labeled Gedatolisib. | ||||
| GC80869 | Calebin A | 336784-82-8 | >98.00% | |
Calebin A is a PI3K/Akt/mTOR, MAPK, and NF-κB inhibitor with oral effectiveness. | ||||
| GC81041 | GP262 | 3107761-81-6 | >98.50% | |
GP262 is a PI3K/mTOR PROTAC degrader targeting PI3Kγ, PI3Kα and mTOR with DC 50 values of 42.23 nM, 227.4 nM and 45.4 nM, respectively in MDA-MB-231 cells. | ||||
| GC81042 | PI3K/mTOR ligand-1 | 1197160-66-9 | >97.00% | |
PI3K/mTOR ligand-1 is a ligand for the target protein of PROTAC ( PI3K / mTOR ). | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81682 | Sialorphin TFA | - | >97.00% | |
Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals. | ||||