Ubiquitination/ Proteasome
Research Areas
Products Related to Ubiquitination/ Proteasome(1333)
- GC78992EAD1 trihydrochloridePurity: >98.00%
EAD1 trihydrochloride is a Chloroquine analog with anticancer activity.
- GC79005AP232 dihydrochloridePurity: >98.00%
AP232 dihydrochloride is a selective U2AF1-UHM Inhibitor with an IC 50 of 7.96 μM.
- GC79046HDAC-IN-98CAS: 3124773-51-6Purity: >98.00%
HDAC-IN-98 is a HDAC1, HDAC2, HDAC3 inhibitor (one of the most selective class I HDAC inhibitors) with human IC 50 values of 41.2 nM, 52.5 nM, and 74.3 nM respectively.
- GC79068Telomeric G4s ligand 2CAS: 3094716-52-3Purity: >98%
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC 50 of 0.4 μM.
- GC79195Semaglutide-FITCPurity: >96.50%
Semaglutide -FITC (Semaglutide-Lys(FITC)) is a fluorescent tracer probe (Ex/Em = 495/520 nm) obtained by covalently coupling the green fluorescent dye fluorescein isothiocyanate (FITC) to the long-acting analogue of GLP-1, Semaglutide.
- GC79196Semaglutide, Cy5 labeledPurity: >98%
Semaglutide, Cy5-labeled (Semaglutide-Cys(Cy5)) is a CY5 -labeled version of Semaglutide (Ex/Em = 633/670 nm).
- GC79733Bz-VGR-AMC TFAPurity: >98.00%
Bz-VGR-AMC TFA is a fluorescent substrate for the trypsin-like activity of the 20S proteasome.
- GC79865Sildenafil-d 3 citratePurity: >98%
Sildenafil-d 3 citrate (UK-92480-d 3 citrate) is the deuterium labeled Sildenafil citrate.
- GC79877Hexestrol-d 4CAS: 91889-42-8Purity: >97.00%
Hexestrol -d 4 is the deuterium labeled Hexestrol.
- GC79989Irinotecan- 13 C 6CAS: 718613-65-1Purity: >98%
Irinotecan - 13 C 6 ((+)-Irinotecan- 13 C 6 ) is the 13 C-labeled Irinotecan.
- GC79990Gemcitabine- 13 C, 15 N 2CAS: 1233921-74-8Purity: >99.00%
antimetabolite and an antineoplastic agent.
- GC79994Cy5-Paclitaxel bromidePurity: >92.50%
Cy5-Paclitaxel bromide is a fluorescently labeled drug probe formed by conjugating the fluorescent dye Cy5 (Cyanine 5) with the chemotherapeutic agent Paclitaxel, which is used to track the cellular uptake, subcellular distribution and drug delivery process of Paclitaxel.
- GC80407Semaglutide-d 8 tetraTFAPurity: >99.50%
Semaglutide -d 8 tetraTFA is the deuterium labeled Semaglutide.
- GC80473Pregnenolone-d 6Purity: >98%
Pregnenolone -d 6 (3β-Hydroxy-5-pregnen-20-one-d 6 ) is the deuterium labeled Pregnenolone [1] . Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones.
- GC80477Sodium butyrate-d 3CAS: 347840-05-5Purity: >99.50%
Sodium butyrate -d 3 (Butanoic acid-d 3 sodium) is the deuterium labeled Sodium butyrate.
- GC80478Acetyl coenzyme A-d 3CAS: 121443-44-5Purity: >98.00%
Acetyl coenzyme A -d 3 (Acetyl-CoA-d 3 ) is the deuterium labeled Acetyl coenzyme A.
- GC80845Spironolactone-d 6 -1Purity: >99.00%
Spironolactone -d 6 -1 is the deuterium labeled Spironolactone.
- GC80883Thalidomide-O-amide-C5-NH2 hydrochlorideCAS: 2716130-28-6Purity: >95.50%
Thalidomide-O-amide-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology [1] [2] .
- GC80919AURKA-IN-4CAS: 89575-11-1Purity: >99.50%
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC78991 | YLRPEGDW | - | >99.00% | |
YLRPEGDW is an orally active sleep-promoting peptide. | ||||
| GC78992 | EAD1 trihydrochloride | - | >98.00% | |
EAD1 trihydrochloride is a Chloroquine analog with anticancer activity. | ||||
| GC78994 | SBP-1750 | 1884219-70-8 | >98.00% | |
SBP-1750 is an orally active ULK inhibitor and an ATG13 degrader. | ||||
| GC79005 | AP232 dihydrochloride | - | >98.00% | |
AP232 dihydrochloride is a selective U2AF1-UHM Inhibitor with an IC 50 of 7.96 μM. | ||||
| GC79046 | HDAC-IN-98 | 3124773-51-6 | >98.00% | |
HDAC-IN-98 is a HDAC1, HDAC2, HDAC3 inhibitor (one of the most selective class I HDAC inhibitors) with human IC 50 values of 41.2 nM, 52.5 nM, and 74.3 nM respectively. | ||||
| GC79057 | BF-175 | 1333375-02-2 | >98% | |
BF-175 is a selective SIRT1 agonist. | ||||
| GC79068 | Telomeric G4s ligand 2 | 3094716-52-3 | >98% | |
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC 50 of 0.4 μM. | ||||
| GC79195 | Semaglutide-FITC | - | >96.50% | |
Semaglutide -FITC (Semaglutide-Lys(FITC)) is a fluorescent tracer probe (Ex/Em = 495/520 nm) obtained by covalently coupling the green fluorescent dye fluorescein isothiocyanate (FITC) to the long-acting analogue of GLP-1, Semaglutide. | ||||
| GC79196 | Semaglutide, Cy5 labeled | - | >98% | |
Semaglutide, Cy5-labeled (Semaglutide-Cys(Cy5)) is a CY5 -labeled version of Semaglutide (Ex/Em = 633/670 nm). | ||||
| GC79519 | SKF-96365 | 162849-90-3 | >99.50% | |
SKF-96365 is a TRPC channel antagonist and store-operated calcium entry ( SOCE ) inhibitor. | ||||
| GC79733 | Bz-VGR-AMC TFA | - | >98.00% | |
Bz-VGR-AMC TFA is a fluorescent substrate for the trypsin-like activity of the 20S proteasome. | ||||
| GC79865 | Sildenafil-d 3 citrate | - | >98% | |
Sildenafil-d 3 citrate (UK-92480-d 3 citrate) is the deuterium labeled Sildenafil citrate. | ||||
| GC79877 | Hexestrol-d 4 | 91889-42-8 | >97.00% | |
Hexestrol -d 4 is the deuterium labeled Hexestrol. | ||||
| GC79989 | Irinotecan- 13 C 6 | 718613-65-1 | >98% | |
Irinotecan - 13 C 6 ((+)-Irinotecan- 13 C 6 ) is the 13 C-labeled Irinotecan. | ||||
| GC79990 | Gemcitabine- 13 C, 15 N 2 | 1233921-74-8 | >99.00% | |
antimetabolite and an antineoplastic agent. | ||||
| GC79994 | Cy5-Paclitaxel bromide | - | >92.50% | |
Cy5-Paclitaxel bromide is a fluorescently labeled drug probe formed by conjugating the fluorescent dye Cy5 (Cyanine 5) with the chemotherapeutic agent Paclitaxel, which is used to track the cellular uptake, subcellular distribution and drug delivery process of Paclitaxel. | ||||
| GC80407 | Semaglutide-d 8 tetraTFA | - | >99.50% | |
Semaglutide -d 8 tetraTFA is the deuterium labeled Semaglutide. | ||||
| GC80408 | Meloxicam- 13 C 6 | - | >98.00% | |
Meloxicam -13C6 is 13 C 6 -labeled Meloxicam. | ||||
| GC80473 | Pregnenolone-d 6 | - | >98% | |
Pregnenolone -d 6 (3β-Hydroxy-5-pregnen-20-one-d 6 ) is the deuterium labeled Pregnenolone [1] . Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. | ||||
| GC80477 | Sodium butyrate-d 3 | 347840-05-5 | >99.50% | |
Sodium butyrate -d 3 (Butanoic acid-d 3 sodium) is the deuterium labeled Sodium butyrate. | ||||
| GC80478 | Acetyl coenzyme A-d 3 | 121443-44-5 | >98.00% | |
Acetyl coenzyme A -d 3 (Acetyl-CoA-d 3 ) is the deuterium labeled Acetyl coenzyme A. | ||||
| GC80845 | Spironolactone-d 6 -1 | - | >99.00% | |
Spironolactone -d 6 -1 is the deuterium labeled Spironolactone. | ||||
| GC80883 | Thalidomide-O-amide-C5-NH2 hydrochloride | 2716130-28-6 | >95.50% | |
Thalidomide-O-amide-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology [1] [2] . | ||||
| GC80919 | AURKA-IN-4 | 89575-11-1 | >99.50% | |
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2. | ||||
