Mitophagy
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Mitophagy is the selective degradation of mitochondria by autophagy.
Mitochondria are essential organelles that regulate cellular energy homeostasis and cell death. The removal of damaged mitochondria through autophagy, a process called mitophagy, is thus critical for maintaining proper cellular functions. Indeed, mitophagy has been recently proposed to play critical roles in terminal differentiation of red blood cells, paternal mitochondrial degradation, neurodegenerative diseases, and ischemia or drug-induced tissue injury.
Autophagy and mitophagy are important cellular processes that are responsible for breaking down cellular contents, preserving energy and safeguarding against accumulation of damaged and aggregated biomolecules.
Products Related to Mitophagy(84)
- GC74187Salicylic acid-13C6CAS: 1189678-81-6Purity: >97.00%
Salicylic acid-13C6 هو حمض الساليسليك الموسوم بـ 13C.
- GC80919AURKA-IN-4CAS: 89575-11-1Purity: >99.50%
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2.
- GN10156Ginsenoside Rb1CAS: 41753-43-9Purity: >98.00%
Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways.
- GN10357ParthenolideCAS: 20554-84-1Purity: >98.00%
Parthenolide is an NF-κB inhibitor with IC 50 values for Eca109, KYSE-510, SiHa and MCF-7 cells of approximately 10.3, 13.3, 8.42 and 9.54µM at 48h respectively.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC71260 | Dox-btn2 | 3026061-31-1 | >97.00% | |
Dox-btn2 هو مشتق بيوتينيلاتيد من الدوكسوروبيسين، مع تسمية البيوتين عند نقطة الاقتران للدوكسوروبيسين عند 3′-NH2. | ||||
| GC71423 | ATTECs Degrader 1 | - | >95.00% | |
ATTECs Degrader 1 (المركب MT1) هو مركب ATTECs. | ||||
| GC71451 | MTX115325 | 2750895-97-5 | >99.00% | |
MTX115325 (مثال 1) هو مثبط USP30 نشط عن طريق الفم (IC50=12 نانومتر) مع نشاط وقائي عصبي. | ||||
| GC71492 | WJ-39 | 3009908-95-3 | >99.00% | |
WJ-39 هو مثبط ALdosreductase النشط عن طريق الفم (AR). | ||||
| GC74187 | Salicylic acid-13C6 | 1189678-81-6 | >97.00% | |
Salicylic acid-13C6 هو حمض الساليسليك الموسوم بـ 13C. | ||||
| GC80919 | AURKA-IN-4 | 89575-11-1 | >99.50% | |
AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2. | ||||
| GC81846 | Nivitol | 869743-37-3 | >98.00% | |
Nivitol (UP302) is a natural phenolic compound discovered from Dianella ensifolia and also acts as a Tyrosinase inhibitor. | ||||
| GN10156 | Ginsenoside Rb1 | 41753-43-9 | >98.00% | |
Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways. | ||||
| GN10257 | Naringin | 10236-47-2 | >99.50% | |
| GN10266 | Quercetin | 117-39-5 | >97.00% | |
الكويرسيتين هو مركب فلافونويد غذائي مهم، يتواجد في الخضروات والفواكه والبذور والمكسرات والشاي والنبيذ الأحمر. | ||||
| GN10331 | Polydatin | 27208-80-6 | >98.00% | |
Polydatin is a natural stilbene glucoside extracted from the traditional Chinese medicine Polygonum cuspidatum , and Polydatin is the glycoside form of resveratrol. | ||||
| GN10357 | Parthenolide | 20554-84-1 | >98.00% | |
Parthenolide is an NF-κB inhibitor with IC 50 values for Eca109, KYSE-510, SiHa and MCF-7 cells of approximately 10.3, 13.3, 8.42 and 9.54µM at 48h respectively. | ||||