ASB 14780 |
| Catalog No.GC50726 |
ASB 14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1069046-00-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor (IC50 = 20 nM). Selective for cPLA2α over secreted PLA2α (sPLA2α; exhibits no inhibition at 10 μM). Inhibits cPLA2α-dependent inflammatory responses in vitro in guinea pig and human whole-blood assays. Improves diet-induced liver injury and CCl4-induced hepatic fibrosis in vivo. Orally bioavailable.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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