GLPBio

Bicyclic UK18

Catalog No.: GC82415Purity:>98.00%
COASDSData Sheet
Bicyclic UK18 is a competitive inhibitor for human urokinase-type plasminogen activator ( uPA ) with a K i of 53 nM [1].

Products are for research use only. Not for human use. We do not sell to patients.

Bicyclic UK18
Cas No.: 1393680-45-9
1mgIn Stock
$122.00
1
5mgIn Stock
$306.00
1
10mgIn Stock
$490.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Bicyclic UK18 is a competitive inhibitor for human urokinase-type plasminogen activator ( uPA ) with a K i of 53 nM [1].

References:
[1]. Angelini A, et al., Bicyclic peptide inhibitor reveals large contact interface with a protease target. ACS Chem Biol. 2012 May 18;7(5):817-21.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1393680-45-9
Molecular Formula
C77H118N26O25S3
Molecular Weight
1904.12
Solubility
DMSO: 100 mg/mL (52.52 mM; Need ultrasonic)
Storage
Sealed storage, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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