Bicyclol |
Catalog No.GC18304 |
Bicyclol is a hepatoprotective agent.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 118159-48-1
Sample solution is provided at 25 µL, 10mM.
Bicyclol is a hepatoprotective agent.,,, It has antiviral activity against hepatitis B (HBV), reducing viral DNA and the secretion of the HBV antigens HBsAg and HBeAg by 59 and 35%, respectively, in infected 2.2.15 HepG2 cells. In vivo, bicyclol reduces duck HBV (DHBV) DNA in DHBV-infected ducks at doses >=0.4 g/kg. It also reduces the expression of TNF-α and the accumulation of lymphocytes in the liver in a mouse model of liver injury induced by concanavalin A . Oral administration of bicyclol prior to injection of diethylnitrosamine (DEN) and phenobarbital prevents formation of DEN/PB-induced hepatocellular carcinomas. It also reduces liver fibrosis in a rat model of bile duct ligation-induced hepatic fibrosis.
Review for Bicyclol
Average Rating: 5
(Based on Reviews and 11 reference(s) in Google Scholar.)Review for Bicyclol
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