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Home >> Signaling Pathways >> Microbiology & Virology >> HBV

HBV

HBV (hepatitis B virus) is a double-strand DNA virus that belongs to the hepadaviridase famlity. It cause transient and acute liver infections which lead to cirrhosis and liver cancer. It is propagated through blood, sex and mother-fetus transmission.

Products for  HBV

  1. Cat.No. Product Name Information
  2. GC65363 (1R)-Tenofovir amibufenamide

    (1R)-HS-10234

     (1R)-Tenofovir amibufenamide ((1R)-HS-10234) is the isomer of Tenofovir amibufenamide, is an orally active antiviral agent. (1R)-Tenofovir amibufenamide Chemical Structure
  3. GC67328 2'-Deoxy-L-adenosine 2'-Deoxy-L-adenosine is an orally active synthon for modified oligodeoxyribonucleotides. 2'-Deoxy-L-adenosine is a potent, specific and selective inhibitor of the replication of hepatitis B virus (HBV) as well as the closely related duck and woodchuck hepatitis viruses (WHV). 2'-Deoxy-L-adenosine Chemical Structure
  4. GC33912 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C)

    4,5-DCQA, Isochlorogenic Acid C

     4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) (Isochlorogenic acid C) is an antioxidant, can be isolated from Gynura divaricata and Laggera alata. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) Chemical Structure
  5. GC39196 4-Hydroxyacetophenone 4-Hydroxyacetophenone (P-hydroxyacetophenone) is a key hepatoprotective and choleretic compound in Artemisia capillaris and A. 4-Hydroxyacetophenone Chemical Structure
  6. GC19014 AB-423 AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 uM/0.33-1.32 uM in cells. AB-423 Chemical Structure
  7. GC68589 AB-836

    AB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits virus replication by interacting with the HBV core protein.

     AB-836 Chemical Structure
  8. GC42731 Adefovir

    GS-0393, PMEA

     Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor. Adefovir Chemical Structure
  9. GC16841 Adefovir Dipivoxil

    GS 0840

     Reverse transcriptase inhibitor Adefovir Dipivoxil Chemical Structure
  10. GC71087 Antiviral agent 38 Antiviral agent 38 (compound 2.1-1) is a potent antiviral agent. Antiviral agent 38 Chemical Structure
  11. GC61821 AT-130 AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 Chemical Structure
  12. GN10377 Aucubin Aucubin Chemical Structure
  13. GC60616 AZT triphosphate

    3'-Azido-3'-deoxythymidine-5'-triphosphate

     AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate Chemical Structure
  14. GC60617 AZT triphosphate TEA

    3'-Azido-3'-deoxythymidine-5'-triphosphate TEA

     AZT triphosphate TEA (3'-Azido-3'-deoxythymidine-5'-triphosphate TEA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA Chemical Structure
  15. GC35454 BA-53038B BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly. BA-53038B Chemical Structure
  16. GC32065 Bay 41-4109 (Bayer 41-4109) BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM. Bay 41-4109 (Bayer 41-4109) Chemical Structure
  17. GC32197 Bay 41-4109 less active enantiomer (Bayer 41-4109 less active enantiomer) Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. Bay 41-4109 less active enantiomer (Bayer 41-4109 less active enantiomer) Chemical Structure
  18. GC32115 Bay 41-4109 racemate An antiviral agent Bay 41-4109 racemate Chemical Structure
  19. GC68297 Bepirovirsen Bepirovirsen Chemical Structure
  20. GC70990 Bepirovirsen sodium Bepirovirsen sodium is an antisense oligonucleotide targeting all HBV messenger RNAs. Bepirovirsen sodium Chemical Structure
  21. GC63421 Bersacapavir

    JNJ-6379; JNJ-56136379

     Bersacapavir is a novel Hepatitis B Virus capsid assembly modulator. Bersacapavir Chemical Structure
  22. GC38517 Besifovir Besifovir (LB80331), a parent drug converted by LB80380, further metabolizes to its active form, LB80317. Besifovir Chemical Structure
  23. GC18304 Bicyclol Bicyclol is a hepatoprotective agent. Bicyclol Chemical Structure
  24. GC39348 Bifendate Bifendate (DDB) is a synthetic intermediate of Schisandrin C with anti-HBV efficacy in research of chronic hepatitis B. Bifendate Chemical Structure
  25. GC68818 Bulevirtide

    Myrcludex B

    Bulevirtide (Myrcludex B) is an NTCP inhibitor and a linear peptide. It can inhibit the entry of HBV and HDV into liver cells, block HBV infection in liver cells, and participate in transcriptional suppression of HBV. Bulevirtide can be used for research on HDV infection and compensated cirrhosis.

     Bulevirtide Chemical Structure
  26. GC68825 Canocapavir

    ZM-H1505R

    Canocapavir (ZM-H1505R) has oral antiviral activity. Canocapavir is an HBV capsid inhibitor that can be used for research on chronic hepatitis B.

     Canocapavir Chemical Structure
  27. GC68843 ccc_R08

    ccc_R08 is a cell-free and orally effective cccDNA inhibitor that can reduce the level of cccDNA in the liver of HBV-infected mice. It can be used for research on HBV (hepatitis B virus) infection.

     ccc_R08 Chemical Structure
  28. GC11689 Cetylpyridinium Chloride

    Hexadecylpyridinium

    Cationic quaternary ammonium compound used as oropharyngeal antiseptic.

     Cetylpyridinium Chloride Chemical Structure
  29. GC68859 Chamaechromone

    Chamaechromone is a flavonoid component isolated from the roots of plants in the thyme family. It has anti-hepatitis B virus (HBV) activity, inhibits the surface secretion antigen (HBsAg) of hepatitis B virus, and also has insecticidal activity.

     Chamaechromone Chemical Structure
  30. GC68870 cis-ccc_R08

    Cis-ccc_R08 (Compound 1) is a flavonoid derivative that can be used for research on hepatitis B virus (HBV) infection. Cis-ccc_R08 is an inhibitor of cccDNA (covalently closed circular DNA).

     cis-ccc_R08 Chemical Structure
  31. GC12635 Clevudine

    Levovir, L-FMAU

     antiviral drug Clevudine Chemical Structure
  32. GC17567 Doxorubicin (Adriamycin) HCl

    DOX

     Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin (Adriamycin) HCl Chemical Structure
  33. GC70994 Elebsiran sodium Elebsiran sodium is a siRNA against hepatitis B and D virus infections . Elebsiran sodium Chemical Structure
  34. GC32093 Entecavir (BMS200475)

    BMS 200475, SQ 34,676

     Entecavir (BMS200475) (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. Entecavir (BMS200475) Chemical Structure
  35. GC16092 Entecavir Hydrate

    BMS 200475, SQ 34,676

     Entecavir Hydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. Entecavir Hydrate Chemical Structure
  36. GC38785 GLP-26 GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 Chemical Structure
  37. GC12555 GS-9620

    Vesatolimod

     A TLR7 agonist GS-9620 Chemical Structure
  38. GC69198 GST-HG131

    GST-HG131 is a specific inhibitor of hepatitis B virus (HBV) surface antigen and belongs to the class of dihydrobenzopyrane (DBP) compounds. It has strong and specific inhibitory effects on HBsAg and HBeAg (EC50=28.2 nM, 16.0 nM). GST-HG131 also exhibits good animal safety.

     GST-HG131 Chemical Structure
  39. GP10047 HBcAg [Hepatitis B virus] (18-27)

    H-Phe-Leu-Pro-Ser-Asp-Phe-Phe-Pro-Ser-Val-OH

    Indicator of active viral replication

     HBcAg [Hepatitis B virus] (18-27) Chemical Structure
  40. GC63003 HBF-0259 HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 Chemical Structure
  41. GC62328 HBV-IN-4 HBV-IN-4, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM. HBV-IN-4 Chemical Structure
  42. GC10418 Helioxanthin

    novel inhibitor of HBV, HCV and HSV-1 virus

     Helioxanthin Chemical Structure
  43. GC13722 Helioxanthin 8-1

    inhibitor of HBV and HIV virus

     Helioxanthin 8-1 Chemical Structure
  44. GC12615 Helioxanthin derivative 5-4-2

    Helioxanthin 5-4-2

     HBV/HSV-1/HSV-2 virus inhibitor Helioxanthin derivative 5-4-2 Chemical Structure
  45. GC36217 Hepatitis B Virus Core 128-140 Hepatitis B Virus Core 128-140 is a peptide of hepatitis B virus core protein. Hepatitis B Virus Core 128-140 Chemical Structure
  46. GC32104 Inarigivir (ORI-9020)

    ORI-9020; SB-9000

     Inarigivir (ORI-9020) (ORI-9020) is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) Chemical Structure
  47. GC63021 Inarigivir ammonium Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir ammonium Chemical Structure
  48. GC61455 IR415 IR415 is a potent anti-HBV agent and inhibits HBV replication by blocking the HBx activity. IR415 Chemical Structure
  49. GN10264 Isochlorogenic acid A

    3,5-DCQA, Isochlorogenic Acid A

     Isochlorogenic acid A Chemical Structure
  50. GC36342 Isoscopoletin

    Esculetin 7-methyl ether, 7-methoxy-6-Hydroxycoumarin, 7-Methoxyesculetin

     A coumarin with diverse biological activities and an active metabolite of scoparone Isoscopoletin Chemical Structure
  51. GC19208 JNJ-632 JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM). JNJ-632 Chemical Structure
  52. GC32287 Lagociclovir (MIV-210) Lagociclovir (MIV-210)(MIV-210) is a prodrug of 3'-fluoro-2',3'-dideoxyguanosine with high oral bioavailability in humans and potent activity against HBV. Lagociclovir (MIV-210) Chemical Structure
  53. GC13522 Merimepodib

    VX-497

     Novel noncompetitive inhibitor of IMPDH(Inosine monophosphate dehydrogenase). Merimepodib Chemical Structure
  54. GC32073 Morphothiadin (GLS4)

    Morphothiadin

     Morphothiadin (GLS4) is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC50 of 12 nM. Morphothiadin (GLS4) Chemical Structure
  55. GC17997 Niranthin antiviral activities, blocking the replication of hepatitis B virus. Niranthin Chemical Structure
  56. GC32144 Osalmid (Oxaphenamide) Osalmid (Oxaphenamide) is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM. Osalmid (Oxaphenamide) Chemical Structure
  57. GC10997 Oxethazaine Topical anesthetic Oxethazaine Chemical Structure
  58. GC62658 PD-1/PD-L1-IN 7

    PD-1/PD-L1-IN 7

     PD-1/PD-L1-IN 7 (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. PD-1/PD-L1-IN 7 Chemical Structure
  59. GN10361 Pseudolaric Acid B

    NSC 615488, PAB

     Pseudolaric Acid B Chemical Structure
  60. GC32193 RG7834 (RO 7020322)

    RO 7020322

     RG7834 (RO 7020322) (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells. RG7834 (RO 7020322) Chemical Structure
  61. GC33932 RIG-1 modulator 1 RIG-1 modulator 1 is an anti-viral compound which can be useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV extracted from patent WO 2015172099 A1. RIG-1 modulator 1 Chemical Structure
  62. GC32071 Squalamine (MSI-1256) Squalamine (MSI-1256)(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity. Squalamine (MSI-1256) Chemical Structure
  63. GP10068 surface antigen (208-215) [Hepatitis B Virus]

    H2N-Ile-Leu-Ser-Pro-Phe-Leu-Pro-Leu-OH

    Surface antigen used for signs of infection

     surface antigen (208-215) [Hepatitis B Virus] Chemical Structure
  64. GC38982 Swertianolin Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin Chemical Structure
  65. GC37740 Taribavirin Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin Chemical Structure
  66. GC38559 Taribavirin hydrochloride Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride Chemical Structure
  67. GC11295 Telbivudine

    2'-deoxy-L-Thymidine, L-Deoxythymidine, NV 02B, β-L-Thymidine

     Reverse Transcriptase inhibitor Telbivudine Chemical Structure
  68. GC12125 Tenofovir

    GS1275, GS1278, (R)PMPA, TDF

    HIV reverse transcriptase inhibitor

     Tenofovir Chemical Structure
  69. GC64918 Tenofovir amibufenamide Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent. Tenofovir amibufenamide Chemical Structure
  70. GC37760 Tenofovir Disoproxil Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Tenofovir Disoproxil Chemical Structure
  71. GC15067 Tenofovir Disoproxil Fumarate

    Bis(POC)-PMPA

     Antiretroviral agent( HIV-1 RT inhibitor) Tenofovir Disoproxil Fumarate Chemical Structure
  72. GC45031 Thiamine (hydrochloride)

    Aneurine, Vitamin B1

     Thiamine is a water-soluble vitamin with antioxidant, neuroprotective, and anxiolytic properties. Thiamine (hydrochloride) Chemical Structure
  73. GC70252 Tiviciclovir hydrochloride Tiviciclovir (AM188) hydrochloride is an antiviral guanosine analog and a hepatitis B virus inhibitor. Tiviciclovir hydrochloride Chemical Structure
  74. GC61339 Torcitabine Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine Chemical Structure
  75. GC70054 trans-ccc_R08

    trans-ccc_R08 (compound 1-B) is an effective inhibitor of cccDNA (covalently closed circular DNA). trans-ccc_R08 inhibits HBeAg levels with an IC50 value of 0.08 µM. trans-ccc_R08 has the potential to be used in research on hepatitis B virus (HBV) infection.

     trans-ccc_R08 Chemical Structure
  76. GC63250 Vebicorvir

    ABI-H0731

     Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir Chemical Structure
  77. GC67195 Vidarabine phosphate

    ara-AMP; ara-A 5'-monophosphate

     Vidarabine phosphate (Ara-AMP), an antiviral agent, inhibits chronic HBV infection. Vidarabine phosphate also against herpes simplex and varicella zoster viruses. Vidarabine phosphate Chemical Structure

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