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BMS-986482 acetate

Catalog No.GC81516 Copy One-Click Copy Product Info

BMS-986482 acetate is a CRBN -mediated IKZF1-4 ( Ikaros family zinc finger 1-4 ) molecular glue degrader.

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BMS-986482 acetate Chemical Structure

Size Price Stock Qty
1mg
$332.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of BMS-986482 acetate

BMS-986482 acetate is a CRBN -mediated IKZF1-4 ( Ikaros family zinc finger 1-4 ) molecular glue degrader. BMS-986482 acetate's activity is driven by a non-traditional CELMoD core that selectively degrades the IKZF protein family. BMS-986482 acetate can be used for the research of advanced solid tumors [1].

In Vivo, BMS-986482 acetate induces robust tumor growth inhibition in syngeneic mouse models[1].

References:
[1]. ACS Spring 2026: First Time Disclosures.

Chemical Properties of BMS-986482 acetate

Cas No. SDF
Formula C23H23FN4O6 M.Wt 470.45
Solubility Storage Store at -20°C, away from moisture
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of BMS-986482 acetate

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1 mg 5 mg 10 mg
1 mM 2.1256 mL 10.6281 mL 21.2562 mL
5 mM 425.1 μL 2.1256 mL 4.2512 mL
10 mM 212.6 μL 1.0628 mL 2.1256 mL
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In vivo Formulation Calculator (Clear solution) of BMS-986482 acetate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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