GLPBio

BMY-25368 hydrochloride

Catalog No.: GC74099Purity:>97.00%Synonyms: SKF 94482 hydrochloride
BMY-25368 drochloride is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.


BMY-25368 hydrochloride
Cas No.: 86134-36-3
1 mgIn Stock
$151.00
1
5 mgIn Stock
$378.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

BMY-25368 drochloride is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor. BMY-25368 drochloride competitively antagonizes gastric secretion stimulated by histamine and also antagonizes gastric secretion stimulated by Pentagastrin , Bethanechol , and food[1].


References:
[1]. Cavanagh RL, et al. Effect of BMY-25368, a potent and long-acting histamine H2-receptor antagonist, on gastric secretion and aspirin-induced gastric lesions in the dog. Aliment Pharmacol Ther. 1989 Jun;3(3):299-313.

Product Documents

Purity:>97.00%Appearance:A solid

Chemical Properties

CAS No.
86134-36-3
Synonyms
SKF 94482 hydrochloride
Molecular Formula
C19H26ClN3O3
Molecular Weight
379.88
Storage
4°C, sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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